Products 99533-80-9

CAS 99533-80-9 appears in our catalog under these names: K252a, K252a, >95% (HPLC), K-252a, K 252a, Protein Kinase Inhibitor K252A . Offered by: Chemat Brand, TRC, TargetMol, GLPBio, Thermo Scientific (Alfa Aesar). Available pack sizes: on request, 0,5mg, 50mg, 5mg, 1mg, 10mg, 100ug, 25mg.

K252a
Chemat Brand, Biosynth
  • size: on request, 5mg, 10mg, 25mg
  • Variants: 4
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K252a, >95% (HPLC)
TRC
  • size: 0,5mg, 50mg, 5mg
  • Variants: 3
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K-252a
TargetMol, Biosynth
  • size: 1mg, 5mg, 25mg
  • Variants: 5
from 1096.64
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K 252a
GLPBio
  • size: 1mg, 5mg
  • Variants: 2
from 784.26
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Protein Kinase Inhibitor K252A
Thermo Scientific (Alfa Aesar)
  • size: 5mg, 1mg
  • Variants: 2
from 762.67
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K-252a, 98.00%
Chemat
  • size: 100ug, 1mg
  • Variants: 2
from 691.83
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K-252a 97%
Ambeed
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 5
from 1310.44
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9,12-Epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, methyl ester, (9S,10R,12R), 97%, 97%
Chemat
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 4
from 875.60
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K-252a, 99.45%
MedChemExpress
  • size: 5 mg, 10mM/1mL, 10 mg, 1 mg
  • Variants: 4
from 793.38
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Structural formula: {0} (CAS {1})

K-252a is a organic heterooctacyclic compound that is a potent inhibitor of protein kinase C and is isolated from Nocardiopsis sp K-252a. It has a role as an antimicrobial agent, an EC 2.7.11.13 (protein kinase C) inhibitor, a bacterial metabolite and a tropomyosin-related kinase B receptor antagonist. It is a methyl ester, a bridged compound, an organic heterooctacyclic compound and a gamma-lactam.

Source: ChEBI

Identity
Molecular formulaC27H21N3O5
Molecular weight467.5 g/mol
IUPAC namemethyl (15S,16R,18R)-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylate
InChIKeyKOZFSFOOLUUIGY-SOLYNIJKSA-N
SMILESC[C@@]12[C@](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)(C(=O)OC)O

Computed by PubChem (NCBI)

Synonyms: k-252a, K252a, Antibiotic K 252a, Antibiotic SF 2370, K 252a, (+)-Antibiotic K 252a, 1r0p, orb1707150, K-252a, from Nocardiopsis sp., 3f69