(2R,3R,4S)-4-(Benzo[d][1,3]dioxol-5-yl)-1-(2-(dibutylamino)-2-oxoethyl)-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid, 99+%

cas: 173937-91-2 — see every product listed under this CAS number, including other names

(2R,3R,4S)-4-(Benzo[d][1,3]dioxol-5-yl)-1-(2-(dibutylamino)-2-oxoethyl)-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid, 99+% (CAS 173937-91-2) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 250mg, 1g. Offered by: BLDpharm.

brandBLDpharm
catalog numberBD630447-100mg
cas173937-91-2
size100mg
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Available pack sizes

brand size price
BLDpharm 100mg 719.77 Pln
BLDpharm 250mg 1297.35 Pln
BLDpharm 1g 3379.95 Pln

properties

purity99+%
delivery time 3-4 weeks
Structural formula: {0} (CAS {1})

Atrasentan is a member of the class of pyrrolidines that is pyrrolidine substituted by 2-(dibutylamino)-2-oxoethyl, 4-methoxyphenyl, carboxy, and 1,3-benzodioxol-5-yl groups at positions 1, 2, 3, and 4, respectively (the 2R,3R,4S-stereoisomer). It is an endothelin endothelin type A receptor antagonist used to reduce proteinuria in adults with primary immunoglobulin A nephropathy. It has a role as an endothelin A receptor antagonist and a nephroprotective agent. It is a tertiary carboxamide, a monomethoxybenzene, a monocarboxylic acid, a member of pyrrolidines, a member of benzodioxoles, a pyrrolidinecarboxylic acid and a tertiary amino compound.

Source: ChEBI

Identity
Molecular formulaC29H38N2O6
Molecular weight510.6 g/mol
IUPAC name(2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid
InChIKeyMOTJMGVDPWRKOC-QPVYNBJUSA-N
SMILESCCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1C2=CC=C(C=C2)OC)C(=O)O)C3=CC4=C(C=C3)OCO4

Computed by PubChem (NCBI)

Synonyms: Atrasentan, atrasentanum, Atrasentan [INN], ATRASENTAN [MI], ATRASENTAN [VANDF], ATRASENTAN [WHO-DD], orb1218632, orb1296093, MOTJMGVDPWRKOC-QPVYNBJUSA-N
Related forms of this compound
(2S,3S,4R)-4-(1,3-benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid C29H38N2O6
(2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid C29H38N2O6
Isomers (same molecular formula)
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxycarbonyl-propan-2-ylamino]hexanoic acid C29H38N2O6
[(1S,2S,6R,14R,15R,16R)-5-cyano-16-(2-hydroxy-3,3-dimethylbutan-2-yl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-yl] ethyl carbonate C29H38N2O6
(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxycarbonyl-propan-2-ylamino]hexanoic acid C29H38N2O6
(1Z,3Z,5R,8S,9S,10S,11S,13R,15R,16R,18Z)-11-ethyl-2,24-dihydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.05,16.08,15.09,13]octacosa-1,3,18-triene-7,20,27,28-tetrone C29H38N2O6
(3E,18Z)-11-ethyl-2,24-dihydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.05,16.08,15.09,13]octacosa-1,3,18-triene-7,20,27,28-tetrone C29H38N2O6
(3R,4R,5S)-4-acetamido-5-[[4-[(3-methoxyphenyl)methoxy]phenyl]methylamino]-3-pentan-3-yloxycyclohexene-1-carboxylic acid C29H38N2O6

Also listed as

(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid, 95% Chemat CAS 173937-91-2
Atrasentan, >95% (HPLC) TRC CAS 173937-91-2
Atrasentan, 99+% AmBeed CAS 173937-91-2
Atrasentan/ 99.08% (existing batch purity) TargetMol CAS 173937-91-2
Atrasentan Biosynth CAS 173937-91-2
Atrasentan, 99.99% MedChemExpress CAS 173937-91-2