Products 173937-91-2
CAS 173937-91-2 appears in our catalog under these names: (2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid, 95%, 95%, Atrasentan, >95% (HPLC), Atrasentan, 99+%, Atrasentan/ 99.08% (existing batch purity), Atrasentan. Offered by: Chemat, TRC, AmBeed, TargetMol, Biosynth. Available pack sizes: 10mg, 50mg, 100mg, 250mg, 1g, 5mg, 25mg, 1mg.
Atrasentan is a member of the class of pyrrolidines that is pyrrolidine substituted by 2-(dibutylamino)-2-oxoethyl, 4-methoxyphenyl, carboxy, and 1,3-benzodioxol-5-yl groups at positions 1, 2, 3, and 4, respectively (the 2R,3R,4S-stereoisomer). It is an endothelin endothelin type A receptor antagonist used to reduce proteinuria in adults with primary immunoglobulin A nephropathy. It has a role as an endothelin A receptor antagonist and a nephroprotective agent. It is a tertiary carboxamide, a monomethoxybenzene, a monocarboxylic acid, a member of pyrrolidines, a member of benzodioxoles, a pyrrolidinecarboxylic acid and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C29H38N2O6 |
|---|---|
| Molecular weight | 510.6 g/mol |
| IUPAC name | (2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid |
| InChIKey | MOTJMGVDPWRKOC-QPVYNBJUSA-N |
| SMILES | CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1C2=CC=C(C=C2)OC)C(=O)O)C3=CC4=C(C=C3)OCO4 |
Computed by PubChem (NCBI)