(5S,8S)-8-(((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, 99%
cas: 552292-08-7 — see every product listed under this CAS number, including other names
(5S,8S)-8-(((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one, 99% (CAS 552292-08-7) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 25mg, 50mg, 100mg, 250mg, 1g. Offered by: BLDpharm.
| brand | BLDpharm |
|---|---|
| catalog number | BD755781-10mg |
| cas | 552292-08-7 |
| size | 10mg |
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| BLDpharm | 10mg | 636.47 Pln | |
| BLDpharm | 25mg | 1075.20 Pln | |
| BLDpharm | 50mg | 1575.03 Pln | |
| BLDpharm | 100mg | 2163.71 Pln | |
| BLDpharm | 250mg | 3213.34 Pln | |
| BLDpharm | 1g | 7933.90 Pln |
properties
| purity | 99% |
|---|---|
| delivery time | 3-4 weeks |
Rolapitant is an azaspiro compound that is 1,7-diazaspiro[4.5]decan-2-one carrying additional phenyl and 1-{[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl substituents at position 8. Used (in the form of the hydrochloride hydrate) for the prevention of delayed nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy. It has a role as an antiemetic and a neurokinin-1 receptor antagonist. It is an ether, a member of piperidines, an azaspiro compound, an organofluorine compound and a member of pyrrolidin-2-ones. It is a conjugate base of a rolapitant(1+).
Source: ChEBI
| Molecular formula | C25H26F6N2O2 |
|---|---|
| Molecular weight | 500.5 g/mol |
| IUPAC name | (5S,8S)-8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-1,9-diazaspiro[4.5]decan-2-one |
| InChIKey | FIVSJYGQAIEMOC-ZGNKEGEESA-N |
| SMILES | C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC[C@]2(CC[C@]3(CCC(=O)N3)CN2)C4=CC=CC=C4 |
Computed by PubChem (NCBI)