(R)–Verapamil hydrochloride

cas: 38176-02-2 — see every product listed under this CAS number, including other names

(R)–Verapamil hydrochloride (CAS 38176-02-2) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 5mg, 50mg. Offered by: GLPBio.

brandGLPBio
catalog numberGC60408-10
cas38176-02-2
size10mg
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Available pack sizes

brand size price
GLPBio 10mg 1977.79 Pln
GLPBio 100mg 8441.56 Pln
GLPBio 5mg 1280.39 Pln
GLPBio 50mg 5188.61 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Dexverapamil hydrochloride is a hydrochloride salt resulting from the reaction of equimolar amounts of dexverapamil and hydrogen chloride. It competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1, EC 3.6.3.44), thereby potentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. Dexverapamil hydrochloride exhibits lower calcium antagonistic activity and toxicity than racemic verapamil hydrochloride. It has a role as an EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor. It contains a dexverapamil(1+). It is an enantiomer of a (S)-verapamil hydrochloride.

Source: ChEBI

Identity
Molecular formulaC27H39ClN2O4
Molecular weight491.1 g/mol
IUPAC name(2R)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile;hydrochloride
InChIKeyDOQPXTMNIUCOSY-HZPIKELBSA-N
SMILESCC(C)[C@@](CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl

Computed by PubChem (NCBI)

Synonyms: Dexverapamil Hydrochloride, (R)-Verapamil Hydrochloride, Verapamil hydrochloride, (+)-, dexverapamil HCl, dexverapamil.HCl, (+)-verapamil hydrochloride, DEXVERAPAMIL MONOHYDROCHLORIDE, VERAPAMIL (R)-FORM HYDROCHLORIDE [MI], r-verapamil hydrochloride, R Verapamil Hydrochloride
Related forms of this compound
2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-(1,1,1,2,3,3,3-heptadeuteriopropan-2-yl)pentanenitrile;hydrochloride C27H39ClN2O4
(2S)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-(trideuteriomethyl)amino]-2-propan-2-ylpentanenitrile;hydrochloride C27H39ClN2O4
(2S)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile;hydrochloride C27H39ClN2O4
(2R)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)pentanenitrile;hydrochloride C27H39ClN2O4
(2S)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-(1,1,1,2,3,3-hexadeuteriopropan-2-yl)pentanenitrile;hydrochloride C27H39ClN2O4
2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-(1,1,1,3,3,3-hexadeuteriopropan-2-yl)pentanenitrile;hydrochloride C27H39ClN2O4
2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-(trideuteriomethyl)amino]-2-propan-2-ylpentanenitrile;hydrochloride C27H39ClN2O4
Isomers (same molecular formula)
2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propylpentanenitrile;hydrochloride C27H39ClN2O4

Also listed as

R-Verapamil HCl Chemat Brand CAS 38176-02-2
S-Verapamil HCl Chemat Brand CAS 38176-02-2
(R)-Verapamil HCl, 98% AmBeed CAS 38176-02-2
(R)-(+)-Verapamil Hydrochloride TRC CAS 38176-02-2
(R)-Verapamil (hydrochloride), 99.37% MedChemExpress CAS 38176-02-2