S-Verapamil HCl

cas: 38176-02-2 — see every product listed under this CAS number, including other names

S-Verapamil HCl (CAS 38176-02-2) is a chemical reagent available from Chemat. Available pack sizes: on request. Offered by: Chemat Brand.

brandChemat Brand
catalog numberULV044
cas38176-02-2
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
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purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Dexverapamil hydrochloride is a hydrochloride salt resulting from the reaction of equimolar amounts of dexverapamil and hydrogen chloride. It competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1, EC 3.6.3.44), thereby potentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. Dexverapamil hydrochloride exhibits lower calcium antagonistic activity and toxicity than racemic verapamil hydrochloride. It has a role as an EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor. It contains a dexverapamil(1+). It is an enantiomer of a (S)-verapamil hydrochloride.

Source: ChEBI

Identity
Molecular formulaC27H39ClN2O4
Molecular weight491.1 g/mol
IUPAC name(2R)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile;hydrochloride
InChIKeyDOQPXTMNIUCOSY-HZPIKELBSA-N
SMILESCC(C)[C@@](CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl

Computed by PubChem (NCBI)

Synonyms: Dexverapamil Hydrochloride, (R)-Verapamil Hydrochloride, Verapamil hydrochloride, (+)-, dexverapamil HCl, dexverapamil.HCl, (+)-verapamil hydrochloride, DEXVERAPAMIL MONOHYDROCHLORIDE, VERAPAMIL (R)-FORM HYDROCHLORIDE [MI], r-verapamil hydrochloride, R Verapamil Hydrochloride
Related forms of this compound
2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-(1,1,1,2,3,3,3-heptadeuteriopropan-2-yl)pentanenitrile;hydrochloride C27H39ClN2O4

Also listed as

R-Verapamil HCl Chemat Brand CAS 38176-02-2
(R)-Verapamil HCl, 98% AmBeed CAS 38176-02-2
(R)-(+)-Verapamil Hydrochloride TRC CAS 38176-02-2
(R)–Verapamil hydrochloride GLPBio CAS 38176-02-2
(R)-Verapamil (hydrochloride), 99.37% MedChemExpress CAS 38176-02-2