Products 38176-02-2
CAS 38176-02-2 appears in our catalog under these names: R-Verapamil HCl, S-Verapamil HCl, (R)-Verapamil HCl, 98%, (R)-(+)-Verapamil Hydrochloride, (R)–Verapamil hydrochloride. Offered by: Chemat Brand, AmBeed, TRC, GLPBio, MedChemExpress. Available pack sizes: on request, 50mg, 100mg, 1mg, 2mg, 5mg, 10mg, 5 mg.
Dexverapamil hydrochloride is a hydrochloride salt resulting from the reaction of equimolar amounts of dexverapamil and hydrogen chloride. It competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1, EC 3.6.3.44), thereby potentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. Dexverapamil hydrochloride exhibits lower calcium antagonistic activity and toxicity than racemic verapamil hydrochloride. It has a role as an EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor. It contains a dexverapamil(1+). It is an enantiomer of a (S)-verapamil hydrochloride.
Source: ChEBI
| Molecular formula | C27H39ClN2O4 |
|---|---|
| Molecular weight | 491.1 g/mol |
| IUPAC name | (2R)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile;hydrochloride |
| InChIKey | DOQPXTMNIUCOSY-HZPIKELBSA-N |
| SMILES | CC(C)[C@@](CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl |
Computed by PubChem (NCBI)