(S)-4-Amino-N-(1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide, 98%

cas: 1143532-39-1 — see every product listed under this CAS number, including other names

(S)-4-Amino-N-(1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide, 98% (CAS 1143532-39-1) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 250mg, 1g. Offered by: BLDpharm.

brandBLDpharm
catalog numberBD287252-1mg
cas1143532-39-1
size1mg
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Available pack sizes

brand size price
BLDpharm 1mg 147.75 Pln
BLDpharm 5mg 258.82 Pln
BLDpharm 10mg 358.79 Pln
BLDpharm 25mg 647.57 Pln
BLDpharm 50mg 941.92 Pln
BLDpharm 100mg 1369.54 Pln
BLDpharm 250mg 1908.24 Pln
BLDpharm 1g 5584.72 Pln
BLDpharm 5g 19385.42 Pln

properties

purity98%
delivery time 1-2 weeks
Structural formula: {0} (CAS {1})

Capivasertib is an aminopiperidine that is piperidine substituted by 7H-pyrrolo[2,3-d]pyrimidin-4-yl, amino, and [(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]aminocarbonyl groups at positions 1, 4, and 4, respectively. It is a pan-AKT kinase inhibitor used in combination with fulvestrant for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer with one or more PIK3CA/AKT1/PTEN-alterations. It has a role as an antineoplastic agent and an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is a secondary carboxamide, a primary alcohol, a pyrrolopyrimidine, an aminopiperidine, a piperidinecarboxamide and a member of monochlorobenzenes.

Source: ChEBI

Identity
Molecular formulaC21H25ClN6O2
Molecular weight428.9 g/mol
IUPAC name4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
InChIKeyJDUBGYFRJFOXQC-KRWDZBQOSA-N
SMILESC1CN(CCC1(C(=O)N[C@@H](CCO)C2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4

Computed by PubChem (NCBI)

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