AZD5363
cas: 1143532-39-1 — see every product listed under this CAS number, including other names
AZD5363 (CAS 1143532-39-1) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 25mg, 5mg, 10mM (in 1ml dmso). Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC11752-100 |
| cas | 1143532-39-1 |
| size | 100mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 100mg | 2291.38 Pln | |
| GLPBio | 25mg | 1051.05 Pln | |
| GLPBio | 5mg | 690.65 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 718.73 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Capivasertib is an aminopiperidine that is piperidine substituted by 7H-pyrrolo[2,3-d]pyrimidin-4-yl, amino, and [(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]aminocarbonyl groups at positions 1, 4, and 4, respectively. It is a pan-AKT kinase inhibitor used in combination with fulvestrant for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer with one or more PIK3CA/AKT1/PTEN-alterations. It has a role as an antineoplastic agent and an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is a secondary carboxamide, a primary alcohol, a pyrrolopyrimidine, an aminopiperidine, a piperidinecarboxamide and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C21H25ClN6O2 |
|---|---|
| Molecular weight | 428.9 g/mol |
| IUPAC name | 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide |
| InChIKey | JDUBGYFRJFOXQC-KRWDZBQOSA-N |
| SMILES | C1CN(CCC1(C(=O)N[C@@H](CCO)C2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4 |
Computed by PubChem (NCBI)