cas: 1143532-39-1 — see every product listed under this CAS number, including other names
Capivasertib, 98% (CAS 1143532-39-1) is a chemical reagent available from Chemat. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 100mg, 250mg, 1g. Offered by: Fluorochem.
| brand | Fluorochem |
|---|---|
| catalog number | F861532-5MG |
| cas | 1143532-39-1 |
| size | 5mg |
| availability | In Stock China |
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| brand | size | price | |
|---|---|---|---|
| Fluorochem | 5mg | 289.50 Pln | |
| Fluorochem | 10mg | 383.22 Pln | |
| Fluorochem | 25mg | 648.75 Pln | |
| Fluorochem | 50mg | 825.77 Pln | |
| Fluorochem | 100mg | 1132.95 Pln | |
| Fluorochem | 250mg | 1809.80 Pln | |
| Fluorochem | 1g | 5704.26 Pln |
| purity | 98% |
|---|---|
| dual use | No |
| currency | EUR |
| delivery time | 3-4 weeks |
| transportryczalt.1 | 50 |
| category | Odczynniki chemiczne |
Capivasertib is an aminopiperidine that is piperidine substituted by 7H-pyrrolo[2,3-d]pyrimidin-4-yl, amino, and [(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]aminocarbonyl groups at positions 1, 4, and 4, respectively. It is a pan-AKT kinase inhibitor used in combination with fulvestrant for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer with one or more PIK3CA/AKT1/PTEN-alterations. It has a role as an antineoplastic agent and an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is a secondary carboxamide, a primary alcohol, a pyrrolopyrimidine, an aminopiperidine, a piperidinecarboxamide and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C21H25ClN6O2 |
|---|---|
| Molecular weight | 428.9 g/mol |
| IUPAC name | 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide |
| InChIKey | JDUBGYFRJFOXQC-KRWDZBQOSA-N |
| SMILES | C1CN(CCC1(C(=O)N[C@@H](CCO)C2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4 |
Computed by PubChem (NCBI)