(S)-PHA533533, 95%

cas: 437982-89-3 — see every product listed under this CAS number, including other names

(S)-PHA533533, 95% (CAS 437982-89-3) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg. Offered by: Ambeed.

brandAmbeed
catalog numberA2766258-1mg
cas437982-89-3
size1mg
Need more information?

Ask us about this product — we're happy to help.

Available pack sizes

brand size price
Ambeed 1mg 1171.38 Pln
Ambeed 5mg 2050.25 Pln
Ambeed 10mg 3646.69 Pln
Ambeed 25mg 6500.25 Pln
Ambeed 50mg 10972.50 Pln

properties

purity95%
delivery time 2-3 weeks
Structural formula: {0} (CAS {1})

PHA-533533 is a carboxamide resulting from the formal condensation of the primary amino group of 5-cyclopropyl-1H-pyrazol-3-amine with the carboxy group of (2S)-2-phenylpropanoic acid in which the phenyl ring is substituted at the para position by a 2-oxopyrrolidin-1-yl group. A CDK2 inhibitor with antineoplastic activity. It has a role as an antineoplastic agent and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is a secondary carboxamide, a tertiary carboxamide, a member of pyrazoles, a member of cyclopropanes and a member of pyrrolidin-2-ones.

Source: ChEBI

Identity
Molecular formulaC19H22N4O2
Molecular weight338.4 g/mol
IUPAC name(2S)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2-oxopyrrolidin-1-yl)phenyl]propanamide
InChIKeyUAOIPNOTWOYAMU-LBPRGKRZSA-N
SMILESC[C@@H](C1=CC=C(C=C1)N2CCCC2=O)C(=O)NC3=NNC(=C3)C4CC4

Computed by PubChem (NCBI)

Synonyms: 3-Aminopyrazole deriv. 13, orb2646349, n-(5-cyclopropyl-1h-pyrazol-3-yl)-2-(4-(2-oxo-1-pyrrolidinyl)phenyl)propanamide
Related forms of this compound
(2R)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2-oxopyrrolidin-1-yl)phenyl]propanamide C19H22N4O2
Isomers (same molecular formula)
6-amino-3-tert-butyl-4-(2-ethoxyphenyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile C19H22N4O2
N-[(2S)-1-[[(E)-3-methylbut-1-enyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide C19H22N4O2
2-[3-(5-phenyltetrazol-2-yl)-1-adamantyl]acetic acid C19H22N4O2
(E)-3-[3-[6-(4-methyl-1,4-diazepan-1-yl)pyrazin-2-yl]phenyl]prop-2-enoic acid C19H22N4O2
2-[4-[(2,5-dimethoxyphenyl)methyl]piperazin-1-yl]pyridine-4-carbonitrile C19H22N4O2
tert-butyl N-(benzotriazol-1-ylmethyl)-N-benzylcarbamate C19H22N4O2
methyl N-[2-[[(2,3-dimethylimidazo[1,2-a]pyridin-8-yl)amino]methyl]-3-methylphenyl]carbamate C19H22N4O2
3-hydroxy-5-(2-methylpropyl)-2-[[4-(1,2,4-triazol-1-yl)phenyl]iminomethyl]cyclohex-2-en-1-one C19H22N4O2
1-N,4-N-diphenyl-1,4-diazepane-1,4-dicarboxamide C19H22N4O2
(2E)-2-[[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)amino]methylidene]-4,4-dimethyl-3-oxopentanenitrile C19H22N4O2
5-(6,7-dimethoxycinnolin-4-yl)-3-methyl-N-propan-2-ylpyridin-2-amine C19H22N4O2

Also listed as

(S)-PHA533533, 98.27% MedChemExpress CAS 437982-89-3
(S)-N-(5-Cyclopropyl-1H-pyrazol-3-yl)-2-(4-(2-oxopyrrolidin-1-yl)phenyl)propanamide, 95% BLDpharm CAS 437982-89-3