Products 437982-89-3
CAS 437982-89-3 appears in our catalog under these names: (S)-PHA533533, 98.27%, (S)-PHA533533, 95%. Offered by: MedChemExpress, Ambeed. Available pack sizes: 50 mg, 1 mg, 25 mg, 5 mg, 10 mg, 10mM/1mL, 1mg, 5mg.
PHA-533533 is a carboxamide resulting from the formal condensation of the primary amino group of 5-cyclopropyl-1H-pyrazol-3-amine with the carboxy group of (2S)-2-phenylpropanoic acid in which the phenyl ring is substituted at the para position by a 2-oxopyrrolidin-1-yl group. A CDK2 inhibitor with antineoplastic activity. It has a role as an antineoplastic agent and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is a secondary carboxamide, a tertiary carboxamide, a member of pyrazoles, a member of cyclopropanes and a member of pyrrolidin-2-ones.
Source: ChEBI
| Molecular formula | C19H22N4O2 |
|---|---|
| Molecular weight | 338.4 g/mol |
| IUPAC name | (2S)-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-[4-(2-oxopyrrolidin-1-yl)phenyl]propanamide |
| InChIKey | UAOIPNOTWOYAMU-LBPRGKRZSA-N |
| SMILES | C[C@@H](C1=CC=C(C=C1)N2CCCC2=O)C(=O)NC3=NNC(=C3)C4CC4 |
Computed by PubChem (NCBI)