(S,E)-4-(Dimethylamino)-N-(4-hydroxy-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide (Afatinib Impurity), 96%

cas: 1456696-14-2 — see every product listed under this CAS number, including other names

(S,E)-4-(Dimethylamino)-N-(4-hydroxy-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide (Afatinib Impurity), 96% (CAS 1456696-14-2) is a chemical reagent available from Chemat. Available pack sizes: 50mg. Offered by: Chemat.

• 2D
• 3D

(E)-4-(dimethylamino)-N-[4-oxo-7-[(3S)-oxolan-3-yl]oxy-3H-quinazolin-6-yl]but-2-enamide (CAS 1456696-14-2) is a chemical compound with the molecular formula C18H22N4O4 and a molecular weight of 358.4 g/mol. IUPAC name: (E)-4-(dimethylamino)-N-[4-oxo-7-[(3S)-oxolan-3-yl]oxy-3H-quinazolin-6-yl]but-2-enamide. InChIKey: GSUSIQVMAQBROU-PCAWENJQSA-N.

Identity

Molecular formula	C18H22N4O4
Molecular weight	358.4 g/mol
IUPAC name	(E)-4-(dimethylamino)-N-[4-oxo-7-[(3S)-oxolan-3-yl]oxy-3H-quinazolin-6-yl]but-2-enamide
InChIKey	GSUSIQVMAQBROU-PCAWENJQSA-N
SMILES	CN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=O)NC=N2)O[C@H]3CCOC3

Computed by PubChem (NCBI)

Synonyms: Afatinib Impurity J, Afatinib Impurity 36, orb3181383, GSUSIQVMAQBROU-PCAWENJQSA-N

Isomers (same molecular formula)

tert-butyl 4-(5-nitroquinolin-8-yl)piperazine-1-carboxylate C₁₈H₂₂N₄O₄

tert-butyl 4-(5-nitroquinolin-6-yl)piperazine-1-carboxylate C₁₈H₂₂N₄O₄

N,N'-bis(2-nitrophenyl)hexane-1,6-diamine C₁₈H₂₂N₄O₄

1-[(2-methylpropan-2-yl)oxycarbonyl]-4-(4-phenyltriazol-1-yl)pyrrolidine-2-carboxylic acid C₁₈H₂₂N₄O₄

2-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]-4-[(4-methoxyphenyl)methylamino]pyrimidine-5-carboxylic acid C₁₈H₂₂N₄O₄

4-(5-aminopentylamino)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione C₁₈H₂₂N₄O₄

2-amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methylbut-1-ynyl)-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide C₁₈H₂₂N₄O₄

2-amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methylbut-1-ynyl)-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide C₁₈H₂₂N₄O₄

ethyl (3S)-3-[[4-(4-carbamimidoylanilino)-4-oxobutanoyl]amino]pent-4-ynoate C₁₈H₂₂N₄O₄

2-amino-1-ethyl-7-[(3R)-3-hydroxy-4-methoxy-3-methylbut-1-ynyl]-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide C₁₈H₂₂N₄O₄

1-[4-[(5-methoxy-3-pyridinyl)oxy]-5-[(3R)-oxan-3-yl]-2-pyridinyl]-3-methylurea C₁₈H₂₂N₄O₄

2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-4-[(4-methoxyphenyl)methylamino]pyrimidine-5-carboxylic acid C₁₈H₂₂N₄O₄