2-Pyridineacetamide, N-[5-[4-[6-[[2-[3-(trifluoromethoxy)phenyl]acetyl]amino]-3-pyridazinyl]butyl]-1,3,4-thiadiazol-2-yl]-, 98%
cas: 1439399-58-2 — see every product listed under this CAS number, including other names
2-Pyridineacetamide, N-[5-[4-[6-[[2-[3-(trifluoromethoxy)phenyl]acetyl]amino]-3-pyridazinyl]butyl]-1,3,4-thiadiazol-2-yl]-, 98% (CAS 1439399-58-2) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 25mg, 50mg, 100mg, 250mg, 500mg, 1g. Offered by: Fluorochem.
| brand | Fluorochem |
|---|---|
| catalog number | F861887-10MG |
| cas | 1439399-58-2 |
| size | 10mg |
| availability | In Stock China |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Fluorochem | 10mg | 174.96 Pln | |
| Fluorochem | 25mg | 263.47 Pln | |
| Fluorochem | 50mg | 414.46 Pln | |
| Fluorochem | 100mg | 669.57 Pln | |
| Fluorochem | 250mg | 1257.91 Pln | |
| Fluorochem | 500mg | 1945.17 Pln | |
| Fluorochem | 1g | 2991.67 Pln |
properties
| purity | 98% |
|---|---|
| dual use | No |
| currency | EUR |
| delivery time | 3-4 weeks |
| category | Odczynniki chemiczne |
Telaglenastat is an orally bioavailable inhibitor of glutaminase, with potential antineoplastic activity. Upon oral administration, CB-839 selectively and irreversibly inhibits glutaminase, a mitochondrial enzyme that is essential for the conversion of the amino acid glutamine into glutamate. By blocking glutamine utilization, proliferation in rapidly growing cells is impaired. Glutamine-dependent tumors rely on the conversion of exogenous glutamine into glutamate and glutamate metabolites to both provide energy and generate building blocks for the production of macromolecules, which are needed for cellular growth and survival. It has a role as an EC 3.5.1.2 (glutaminase) inhibitor.
Source: ChEBI
| Molecular formula | C26H24F3N7O3S |
|---|---|
| Molecular weight | 571.6 g/mol |
| IUPAC name | N-[6-[4-[5-[(2-pyridin-2-ylacetyl)amino]-1,3,4-thiadiazol-2-yl]butyl]pyridazin-3-yl]-2-[3-(trifluoromethoxy)phenyl]acetamide |
| InChIKey | PRAAPINBUWJLGA-UHFFFAOYSA-N |
| SMILES | C1=CC=NC(=C1)CC(=O)NC2=NN=C(S2)CCCCC3=NN=C(C=C3)NC(=O)CC4=CC(=CC=C4)OC(F)(F)F |
Computed by PubChem (NCBI)