6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo(3,4-b)(1,3,4)thiadiazole

cas: 577696-37-8 — see every product listed under this CAS number, including other names

6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo(3,4-b)(1,3,4)thiadiazole (CAS 577696-37-8) is a chemical reagent available from Chemat. Available pack sizes: 100mg. Offered by: TRC.

brandTRC
catalog numberTRC-C987855-100MG
cas577696-37-8
size100mg
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purityNo data
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Structural formula: {0} (CAS {1})

Cardionogen-1 is a triazolothiadiazole that is [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole which is substituted at positions 3 and 6 by 2-furyl and cyclohexyl groups, respectively. A cardiomyocyte promoter and an inhibitor of Wnt/beta-catenin dependent transcriptional activity, it induces cardiac cell formation in murine stem cells and zebrafish embryos, expanding cardiac progenitor cells. A biphasic modulator of cardiogenesis, it can act as either a promotor or inhibitor of heart formation, depending on the stage of treatment. It has a role as a Wnt signalling inhibitor. It is a triazolothiadiazole and a member of furans.

Source: ChEBI

Identity
Molecular formulaC13H14N4OS
Molecular weight274.34 g/mol
IUPAC name6-cyclohexyl-3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
InChIKeySWTUPSNBTSPBIH-UHFFFAOYSA-N
SMILESC1CCC(CC1)C2=NN3C(=NN=C3S2)C4=CC=CO4

Computed by PubChem (NCBI)

Synonyms: vuc230, 6-cyclohexyl-3-furan-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole, 6-cyclohexyl-3-furan-2-yl-(1,2,4)triazolo(3,4-b)(1,3,4)thiadiazole, Cardionogen 1, cardionogen-1, 6-cyclohexyl-3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole, 6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole, 1,2,4-Triazolo(3,4-b)(1,3,4)thiadiazole, 6-cyclohexyl-3-(2-furanyl)-, 6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo(3,4-b)(1,3,4)thiadiazole, 6-cyclohexyl-3-(2-furyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
Isomers (same molecular formula)
4-amino-N-benzyl-2-methylsulfanylpyrimidine-5-carboxamide C13H14N4OS
4-(5-amino-1,3,4-thiadiazol-2-yl)-1-(2-methylphenyl)pyrrolidin-2-one C13H14N4OS
N-phenyl-5-pyrrolidin-2-yl-1,3,4-thiadiazole-2-carboxamide C13H14N4OS
2,4-diamino-7-(5-methylthiophen-2-yl)-7,8-dihydro-6H-quinazolin-5-one C13H14N4OS
4-(5-amino-1,3,4-thiadiazol-2-yl)-1-(4-methylphenyl)pyrrolidin-2-one C13H14N4OS
1-[4-(2-amino-4-methyl-1,3-thiazol-5-yl)-2-pyridinyl]cyclopropane-1-carboxamide C13H14N4OS
4-[(4-methylpyrimidin-2-yl)sulfanylmethyl]benzohydrazide C13H14N4OS
N-[3-(3-cyclopropyl-5-sulfanylidene-1H-1,2,4-triazol-4-yl)phenyl]acetamide C13H14N4OS
4-butyl-1-sulfanylidene-2H-[1,2,4]triazolo[4,3-a]quinazolin-5-one C13H14N4OS
1-(2-hydroxy-1-methylindol-3-yl)imino-3-prop-2-enylthiourea C13H14N4OS
(4-pyrimidin-2-ylpiperazin-1-yl)-thiophen-2-ylmethanone C13H14N4OS
4-[(5-methylpyrimidin-2-yl)sulfanylmethyl]benzohydrazide C13H14N4OS

Also listed as

Cardionogen 1 GLPBio CAS 577696-37-8
Cardionogen 1 Biosynth CAS 577696-37-8
Cardionogen 1, 99.21% MedChemExpress CAS 577696-37-8
6-cyclohexyl-3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole, 99% Chemat CAS 577696-37-8