Products 577696-37-8
CAS 577696-37-8 appears in our catalog under these names: 6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo(3,4-b)(1,3,4)thiadiazole, Cardionogen 1, Cardionogen 1, 6-cyclohexyl-3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole, 99%, 99%, Cardionogen 1, 99.21%. Offered by: TRC, GLPBio, Biosynth, Chemat, MedChemExpress. Available pack sizes: 100mg, 10mg, 50mg, 5mg, 25mg, 1mg, 1 mg.
Cardionogen-1 is a triazolothiadiazole that is [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole which is substituted at positions 3 and 6 by 2-furyl and cyclohexyl groups, respectively. A cardiomyocyte promoter and an inhibitor of Wnt/beta-catenin dependent transcriptional activity, it induces cardiac cell formation in murine stem cells and zebrafish embryos, expanding cardiac progenitor cells. A biphasic modulator of cardiogenesis, it can act as either a promotor or inhibitor of heart formation, depending on the stage of treatment. It has a role as a Wnt signalling inhibitor. It is a triazolothiadiazole and a member of furans.
Source: ChEBI
| Molecular formula | C13H14N4OS |
|---|---|
| Molecular weight | 274.34 g/mol |
| IUPAC name | 6-cyclohexyl-3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole |
| InChIKey | SWTUPSNBTSPBIH-UHFFFAOYSA-N |
| SMILES | C1CCC(CC1)C2=NN3C(=NN=C3S2)C4=CC=CO4 |
Computed by PubChem (NCBI)
Synonyms:
vuc230, 6-cyclohexyl-3-furan-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole, 6-cyclohexyl-3-furan-2-yl-(1,2,4)triazolo(3,4-b)(1,3,4)thiadiazole, Cardionogen 1, cardionogen-1, 6-cyclohexyl-3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole, 6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole, 1,2,4-Triazolo(3,4-b)(1,3,4)thiadiazole, 6-cyclohexyl-3-(2-furanyl)-, 6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo(3,4-b)(1,3,4)thiadiazole, 6-cyclohexyl-3-(2-furyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole