6-Methoxy-2-(5-methylfuran-2-yl)-N-(1-methylpiperidin-4-yl)-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-amine, 98%, 98%

cas: 1846570-31-7 — see every product listed under this CAS number, including other names

6-Methoxy-2-(5-methylfuran-2-yl)-N-(1-methylpiperidin-4-yl)-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-amine, 98%, 98% (CAS 1846570-31-7) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg. Offered by: Chemat.

brandChemat
catalog numberCh12LICB-1mg
cas1846570-31-7
size1mg
availability 0.2g
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Available pack sizes

brand size price
Chemat 1mg 122.00 Pln
Chemat 5mg 218.00 Pln
Chemat 10mg 328.40 Pln
Chemat 25mg 597.20 Pln
Chemat 50mg 914.00 Pln
Chemat 100mg 1427.60 Pln

properties

purity98%
delivery time3 weeks
Structural formula: {0} (CAS {1})

CM-272 is a member of the class of aminoquinolines that is is quinoline substituted by 5-methylfuran-2-yl, (1-methylpiperidin-4-yl)amino, methoxy, and 3-(pyrrolidin-1-yl)propoxy groups at positions 2, 4, 6 and 7, respectively. It is a dual G9a/DNA methyltransferases inhibitor with antitumor activity. It inhibits G9a, DNMT1, DNMT3A, DNMT3B and GLP (IC50 = 8 nM, 382 nM, 85 nM, 1200 nM and 2 nM, respectively). It has a role as an EC 2.1.1.43 (enhancer of zeste homolog 2) inhibitor, a ferroptosis inducer, an antineoplastic agent, an apoptosis inducer and an EC 2.1.1.37 [DNA (cytosine-5-)-methyltransferase] inhibitor. It is a member of furans, a member of piperidines, an aromatic ether, an aminoquinoline, a N-alkylpyrrolidine, a diether, a secondary amino compound and a tertiary amino compound.

Source: ChEBI

Identity
Molecular formulaC28H38N4O3
Molecular weight478.6 g/mol
IUPAC name6-methoxy-2-(5-methylfuran-2-yl)-N-(1-methylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinolin-4-amine
InChIKeyRLQLKZTYUYIWDB-UHFFFAOYSA-N
SMILESCC1=CC=C(O1)C2=NC3=CC(=C(C=C3C(=C2)NC4CCN(CC4)C)OC)OCCCN5CCCC5

Computed by PubChem (NCBI)

Synonyms: 1846570-31-7 (free base), orb1225855, orb1299991, s8812

Also listed as

CM–272 GLPBio CAS 1846570-31-7
CM-272/ 98.21% (existing batch purity) TargetMol CAS 1846570-31-7
CM-272 Biosynth CAS 1846570-31-7
CM-272, 98.70% MedChemExpress CAS 1846570-31-7
CM-272 (Standard) MedChemExpress CAS 1846570-31-7
6-methoxy-2-(5-methyl-2-furanyl)-N-(1-methyl-4-piperidinyl)-7-[3-(1-pyrrolidinyl)propoxy]-4-quinolinamine, 98% Fluorochem CAS 1846570-31-7
CM-272, 98% Ambeed CAS 1846570-31-7