ACP–196
cas: 1420477-60-6 — see every product listed under this CAS number, including other names
ACP–196 (CAS 1420477-60-6) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 25mg, 5mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC15453-100 |
| cas | 1420477-60-6 |
| size | 100mg |
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 100mg | 1996.51 Pln | |
| GLPBio | 25mg | 1275.71 Pln | |
| GLPBio | 5mg | 625.12 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Acalabrutinib is a member of the class of imidazopyrazines that is imidazo[1,5-a]pyrazine substituted by 4-(pyridin-2-ylcarbamoyl)phenyl, (2S)-1-(but-2-ynoyl)pyrrolidin-2-yl, and amino groups at positions 1, 3 and 8, respectively. It is an irreversible second-generation Bruton's tyrosine kinase (BTK) inhibitor that is approved by the FDA for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. It has a role as an antineoplastic agent, an apoptosis inducer and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a secondary carboxamide, a tertiary carboxamide, a member of benzamides, a member of pyridines, an aromatic amine, an imidazopyrazine, a pyrrolidinecarboxamide and a ynone.
Source: ChEBI
| Molecular formula | C26H23N7O2 |
|---|---|
| Molecular weight | 465.5 g/mol |
| IUPAC name | 4-[8-amino-3-[(2S)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide |
| InChIKey | WDENQIQQYWYTPO-IBGZPJMESA-N |
| SMILES | CC#CC(=O)N1CCC[C@H]1C2=NC(=C3N2C=CN=C3N)C4=CC=C(C=C4)C(=O)NC5=CC=CC=N5 |
Computed by PubChem (NCBI)