Acalabrutinib (Standard)
cas: 1420477-60-6 — see every product listed under this CAS number, including other names
Acalabrutinib (Standard) (CAS 1420477-60-6) is a chemical reagent available from Chemat. Available pack sizes: 50 mg, 25 mg, 5 mg, 10 mg, 100 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-17600R-50 mg |
| cas | 1420477-60-6 |
| size | 50 mg |
| availability | Get quote |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 50 mg | 2000.82 Pln | |
| MedChemExpress | 25 mg | 1462.12 Pln | |
| MedChemExpress | 5 mg | 719.08 Pln | |
| MedChemExpress | 10 mg | 960.56 Pln | |
| MedChemExpress | 100 mg | 2748.50 Pln |
properties
| delivery time | over 3 weeks |
|---|---|
| purity | no data |
Acalabrutinib is a member of the class of imidazopyrazines that is imidazo[1,5-a]pyrazine substituted by 4-(pyridin-2-ylcarbamoyl)phenyl, (2S)-1-(but-2-ynoyl)pyrrolidin-2-yl, and amino groups at positions 1, 3 and 8, respectively. It is an irreversible second-generation Bruton's tyrosine kinase (BTK) inhibitor that is approved by the FDA for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. It has a role as an antineoplastic agent, an apoptosis inducer and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a secondary carboxamide, a tertiary carboxamide, a member of benzamides, a member of pyridines, an aromatic amine, an imidazopyrazine, a pyrrolidinecarboxamide and a ynone.
Source: ChEBI
| Molecular formula | C26H23N7O2 |
|---|---|
| Molecular weight | 465.5 g/mol |
| IUPAC name | 4-[8-amino-3-[(2S)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide |
| InChIKey | WDENQIQQYWYTPO-IBGZPJMESA-N |
| SMILES | CC#CC(=O)N1CCC[C@H]1C2=NC(=C3N2C=CN=C3N)C4=CC=C(C=C4)C(=O)NC5=CC=CC=N5 |
Computed by PubChem (NCBI)