AS-703026, 98%, 98%
cas: 1236699-92-5 — see every product listed under this CAS number, including other names
AS-703026, 98%, 98% (CAS 1236699-92-5) is a chemical reagent available from Chemat. Available pack sizes: 5mg, 10mg, 50mg, 100mg, 250mg, 1g. Offered by: Chemat.
| brand | Chemat |
|---|---|
| catalog number | Ch111KXC-5mg |
| cas | 1236699-92-5 |
| size | 5mg |
| availability | 2g |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat | 5mg | 160.40 Pln | |
| Chemat | 10mg | 208.40 Pln | |
| Chemat | 50mg | 227.60 Pln | |
| Chemat | 100mg | 342.80 Pln | |
| Chemat | 250mg | 539.60 Pln | |
| Chemat | 1g | 1350.80 Pln |
properties
| purity | 98% |
|---|---|
| delivery time | 3 weeks |
Pimasertib is a secondary carboxamide resulting from the formal condensation of the carboxy group of 3-(2-fluoro-4-iodoanilino)pyridine-4-carboxylic acid with the amino group of (2S)-3-aminopropane-1,2-diol. It is a potent inhibitor of the mitogen-activated protein kinases MEK1 and MEK2 with potential antineoplastic activity. It has a role as an antineoplastic agent, an apoptosis inducer and an EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor. It is a secondary carboxamide, a primary alcohol, a diol, a pyridinecarboxamide, a secondary alcohol, an aminopyridine, a difluorobenzene and a substituted aniline.
Source: ChEBI
| Molecular formula | C15H15FIN3O3 |
|---|---|
| Molecular weight | 431.20 g/mol |
| IUPAC name | N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide |
| InChIKey | VIUAUNHCRHHYNE-JTQLQIEISA-N |
| SMILES | C1=CC(=C(C=C1I)F)NC2=C(C=CN=C2)C(=O)NC[C@@H](CO)O |
Computed by PubChem (NCBI)
Synonyms:
Pimasertib, N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide, pimasertibum, N-((2S)-2,3-dihydroxypropyl)-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide, Msc1936369a; as703026; emd 1036239, Pimasertib (AS-703026), (S)-N-(2,3-dihydroxypropyl)-3-((2-fluoro-4-iodophenyl)amino)isonicotinamide, N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodo-anilino)pyridine-4-carboxamide, (S)-N-(2,3-dihydroxypropyl)-3-(2-fluoro-4-iodophenylamino)isonicotinamide, Pimasertib [INN]