AS-703026

cas: 1236699-92-5 — see every product listed under this CAS number, including other names

AS-703026 (CAS 1236699-92-5) is a chemical reagent available from Chemat. Available pack sizes: 250mg, 10mg, 1mg, 5mg. Offered by: TRC, Chemat.

brandTRC
catalog numberTRC-A780100-250MG
cas1236699-92-5
size250mg
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Available pack sizes

brand size price
TRC 250mg price on request
Chemat 10mg 1426.15 Pln
Chemat 1mg 777.98 Pln
Chemat 5mg 1102.07 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Pimasertib is a secondary carboxamide resulting from the formal condensation of the carboxy group of 3-(2-fluoro-4-iodoanilino)pyridine-4-carboxylic acid with the amino group of (2S)-3-aminopropane-1,2-diol. It is a potent inhibitor of the mitogen-activated protein kinases MEK1 and MEK2 with potential antineoplastic activity. It has a role as an antineoplastic agent, an apoptosis inducer and an EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor. It is a secondary carboxamide, a primary alcohol, a diol, a pyridinecarboxamide, a secondary alcohol, an aminopyridine, a difluorobenzene and a substituted aniline.

Source: ChEBI

Identity
Molecular formulaC15H15FIN3O3
Molecular weight431.20 g/mol
IUPAC nameN-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide
InChIKeyVIUAUNHCRHHYNE-JTQLQIEISA-N
SMILESC1=CC(=C(C=C1I)F)NC2=C(C=CN=C2)C(=O)NC[C@@H](CO)O

Computed by PubChem (NCBI)

Synonyms: Pimasertib, N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide, pimasertibum, N-((2S)-2,3-dihydroxypropyl)-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide, Msc1936369a; as703026; emd 1036239, Pimasertib (AS-703026), (S)-N-(2,3-dihydroxypropyl)-3-((2-fluoro-4-iodophenyl)amino)isonicotinamide, N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodo-anilino)pyridine-4-carboxamide, (S)-N-(2,3-dihydroxypropyl)-3-(2-fluoro-4-iodophenylamino)isonicotinamide, Pimasertib [INN]
Related forms of this compound
3-(2-fluoro-4-iodoanilino)-N-(1,1,2,3,3-pentadeuterio-2,3-dihydroxypropyl)pyridine-4-carboxamide C15H15FIN3O3

Also listed as

Pimasertib (AS–703026) GLPBio CAS 1236699-92-5
Pimasertib/ 98.15% (existing batch purity) TargetMol CAS 1236699-92-5
Pimasertib Biosynth CAS 1236699-92-5
Pimasertib 98% Ambeed CAS 1236699-92-5
AS-703026, 98%, 98% Chemat CAS 1236699-92-5
Pimasertib, 99.60% MedChemExpress CAS 1236699-92-5
Pimasertib, 98% Fluorochem CAS 1236699-92-5