Pimasertib (AS–703026)

cas: 1236699-92-5 — see every product listed under this CAS number, including other names

Pimasertib (AS–703026) (CAS 1236699-92-5) is a chemical reagent available from Chemat. Available pack sizes: 5mg, 10mg, 100mg, 25mg, 10mM (in 1ml dmso). Offered by: GLPBio.

brandGLPBio
catalog numberGC18050-5
cas1236699-92-5
size5mg
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Available pack sizes

brand size price
GLPBio 5mg 578.32 Pln
GLPBio 10mg 620.44 Pln
GLPBio 100mg 1411.45 Pln
GLPBio 25mg 812.34 Pln
GLPBio 10mM (in 1ml dmso) 606.40 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Pimasertib is a secondary carboxamide resulting from the formal condensation of the carboxy group of 3-(2-fluoro-4-iodoanilino)pyridine-4-carboxylic acid with the amino group of (2S)-3-aminopropane-1,2-diol. It is a potent inhibitor of the mitogen-activated protein kinases MEK1 and MEK2 with potential antineoplastic activity. It has a role as an antineoplastic agent, an apoptosis inducer and an EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor. It is a secondary carboxamide, a primary alcohol, a diol, a pyridinecarboxamide, a secondary alcohol, an aminopyridine, a difluorobenzene and a substituted aniline.

Source: ChEBI

Identity
Molecular formulaC15H15FIN3O3
Molecular weight431.20 g/mol
IUPAC nameN-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide
InChIKeyVIUAUNHCRHHYNE-JTQLQIEISA-N
SMILESC1=CC(=C(C=C1I)F)NC2=C(C=CN=C2)C(=O)NC[C@@H](CO)O

Computed by PubChem (NCBI)

Synonyms: Pimasertib, N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide, pimasertibum, N-((2S)-2,3-dihydroxypropyl)-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide, Msc1936369a; as703026; emd 1036239, Pimasertib (AS-703026), (S)-N-(2,3-dihydroxypropyl)-3-((2-fluoro-4-iodophenyl)amino)isonicotinamide, N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodo-anilino)pyridine-4-carboxamide, (S)-N-(2,3-dihydroxypropyl)-3-(2-fluoro-4-iodophenylamino)isonicotinamide, Pimasertib [INN]
Related forms of this compound
3-(2-fluoro-4-iodoanilino)-N-(1,1,2,3,3-pentadeuterio-2,3-dihydroxypropyl)pyridine-4-carboxamide C15H15FIN3O3

Also listed as

AS-703026 TRC CAS 1236699-92-5
Pimasertib/ 98.15% (existing batch purity) TargetMol CAS 1236699-92-5
Pimasertib Biosynth CAS 1236699-92-5
Pimasertib 98% Ambeed CAS 1236699-92-5
AS-703026, 98%, 98% Chemat CAS 1236699-92-5
Pimasertib, 99.60% MedChemExpress CAS 1236699-92-5
Pimasertib, 98% Fluorochem CAS 1236699-92-5