AZD2858, 99.44%
cas: 486424-20-8 — see every product listed under this CAS number, including other names
AZD2858, 99.44% (CAS 486424-20-8) is a chemical reagent available from Chemat. Available pack sizes: 10mM/1mL, 25 mg, 100 mg, 10 mg, 50 mg, 5 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-15761-10mM/1mL |
| cas | 486424-20-8 |
| size | 10mM/1mL |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 10mM/1mL | 876.97 Pln | |
| MedChemExpress | 25 mg | 1225.27 Pln | |
| MedChemExpress | 100 mg | 2520.95 Pln | |
| MedChemExpress | 10 mg | 811.96 Pln | |
| MedChemExpress | 50 mg | 1847.57 Pln | |
| MedChemExpress | 5 mg | 561.18 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.44% |
AZD2858 is a member of the class of pyrazines that is pyrazine substituted by (pyridin-3-yl)aminocarbonyl, amino, and 4-(4-methylpiperazine-1-sulfonyl)phenyl groups at positions 2, 3 and 6, respectively. It is a potent inhibitor of GSK3alpha and GSK3beta (IC50 values of 0.9 and 4.9 nM, respectively) and increases bone mass (via Wnt activation) in rats. It has a role as a Wnt signalling activator, an antineoplastic agent, a bone density conservation agent and an EC 2.7.11.26 (tau-protein kinase) inhibitor. It is a secondary carboxamide, a member of pyridines, an aromatic amine, a sulfonamide, a member of pyrazines and a N-methylpiperazine.
Source: ChEBI
| Molecular formula | C21H23N7O3S |
|---|---|
| Molecular weight | 453.5 g/mol |
| IUPAC name | 3-amino-6-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]-N-pyridin-3-ylpyrazine-2-carboxamide |
| InChIKey | FHCSBLWRGCOVPT-UHFFFAOYSA-N |
| SMILES | CN1CCN(CC1)S(=O)(=O)C2=CC=C(C=C2)C3=CN=C(C(=N3)C(=O)NC4=CN=CC=C4)N |
Computed by PubChem (NCBI)