AZD2858
cas: 486424-20-8 — see every product listed under this CAS number, including other names
AZD2858 (CAS 486424-20-8) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC14736-10 |
| cas | 486424-20-8 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 746.82 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 863.83 Pln | |
| GLPBio | 50mg | 1715.68 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
AZD2858 is a member of the class of pyrazines that is pyrazine substituted by (pyridin-3-yl)aminocarbonyl, amino, and 4-(4-methylpiperazine-1-sulfonyl)phenyl groups at positions 2, 3 and 6, respectively. It is a potent inhibitor of GSK3alpha and GSK3beta (IC50 values of 0.9 and 4.9 nM, respectively) and increases bone mass (via Wnt activation) in rats. It has a role as a Wnt signalling activator, an antineoplastic agent, a bone density conservation agent and an EC 2.7.11.26 (tau-protein kinase) inhibitor. It is a secondary carboxamide, a member of pyridines, an aromatic amine, a sulfonamide, a member of pyrazines and a N-methylpiperazine.
Source: ChEBI
| Molecular formula | C21H23N7O3S |
|---|---|
| Molecular weight | 453.5 g/mol |
| IUPAC name | 3-amino-6-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]-N-pyridin-3-ylpyrazine-2-carboxamide |
| InChIKey | FHCSBLWRGCOVPT-UHFFFAOYSA-N |
| SMILES | CN1CCN(CC1)S(=O)(=O)C2=CC=C(C=C2)C3=CN=C(C(=N3)C(=O)NC4=CN=CC=C4)N |
Computed by PubChem (NCBI)