AZD5363, 98%, 98%

cas: 1143532-39-1 — see every product listed under this CAS number, including other names

AZD5363, 98%, 98% (CAS 1143532-39-1) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 250mg, 1g. Offered by: Chemat.

brandChemat
catalog numberCh111B5O-1mg
cas1143532-39-1
size1mg
availability 9.723g
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Available pack sizes

brand size price
Chemat 1mg 112.40 Pln
Chemat 5mg 179.60 Pln
Chemat 10mg 237.20 Pln
Chemat 25mg 395.60 Pln
Chemat 50mg 501.20 Pln
Chemat 100mg 678.80 Pln
Chemat 250mg 1086.80 Pln
Chemat 1g 3419.60 Pln
Chemat 5g 10139.60 Pln

properties

purity98%
delivery time3 weeks
Structural formula: {0} (CAS {1})

Capivasertib is an aminopiperidine that is piperidine substituted by 7H-pyrrolo[2,3-d]pyrimidin-4-yl, amino, and [(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]aminocarbonyl groups at positions 1, 4, and 4, respectively. It is a pan-AKT kinase inhibitor used in combination with fulvestrant for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer with one or more PIK3CA/AKT1/PTEN-alterations. It has a role as an antineoplastic agent and an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is a secondary carboxamide, a primary alcohol, a pyrrolopyrimidine, an aminopiperidine, a piperidinecarboxamide and a member of monochlorobenzenes.

Source: ChEBI

Identity
Molecular formulaC21H25ClN6O2
Molecular weight428.9 g/mol
IUPAC name4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
InChIKeyJDUBGYFRJFOXQC-KRWDZBQOSA-N
SMILESC1CN(CCC1(C(=O)N[C@@H](CCO)C2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4

Computed by PubChem (NCBI)

Synonyms: capivasertib, Truqap, capivasertibum, Capivasertib (AZD5363), C21H25ClN6O2, cc-638, s8019, Truqap (TN), Capivasertib (JAN/USAN), CAPIVASERTIB [INN]
Related forms of this compound
4-amino-N-[(1R)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide C21H25ClN6O2

Also listed as

AZD5363, >95% (HPLC) TRC CAS 1143532-39-1
Capivasertib/ 98.96% (existing batch purity) TargetMol CAS 1143532-39-1
AZD5363 GLPBio CAS 1143532-39-1
AZD 5363 Biosynth CAS 1143532-39-1
Capivasertib, 99.96% MedChemExpress CAS 1143532-39-1
Capivasertib (Standard) MedChemExpress CAS 1143532-39-1
Capivasertib, 98% Ambeed CAS 1143532-39-1