Axitinib
cas: 319460-85-0 — see every product listed under this CAS number, including other names
Axitinib (CAS 319460-85-0) is a chemical reagent available from Chemat. Available pack sizes: on request, 250mg, 100mg, 1g, 500mg, 1000mg, 2000mg. Offered by: Chemat Brand, Mikromol, Biosynth, Thermo Scientific (Acros).
| brand | Chemat Brand |
|---|---|
| catalog number | ULA188008 |
| cas | 319460-85-0 |
| size | on request |
| availability | Do potwierdzenia przez Chemat|To be confirmed by Chemat |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat Brand | on request | price on request | |
| Chemat Brand | on request | price on request | |
| Mikromol | 250mg | price on request | |
| Biosynth | 250mg | price on request | |
| Biosynth | 100mg | price on request | |
| Thermo Scientific (Acros) | 1g | 1821.87 Pln | |
| Thermo Scientific (Acros) | 250MG | 939.89 Pln | |
| Biosynth | 500mg | price on request | |
| Biosynth | 1000mg | price on request | |
| Biosynth | 2000mg | price on request |
properties
| purity | No data |
|---|---|
| category | Chemicals |
| delivery time | To be confirmed by Chemat |
Axitinib is an indazole substituted at position 3 by a 2-(pyridin-2-yl)vinyl group and at position 6 by a 2-(N-methylaminocarboxy)phenylsulfanyl group. Used for the treatment of advanced renal cell carcinoma after failure of a first line systemic treatment. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor and a vascular endothelial growth factor receptor antagonist. It is a member of benzamides, a member of pyridines, an aryl sulfide and a member of indazoles.
Source: ChEBI
| Molecular formula | C22H18N4OS |
|---|---|
| Molecular weight | 386.5 g/mol |
| IUPAC name | N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide |
| InChIKey | RITAVMQDGBJQJZ-FMIVXFBMSA-N |
| SMILES | CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)/C=C/C4=CC=CC=N4 |
Computed by PubChem (NCBI)
Synonyms:
Axitinib, Inlyta, axitinibum, N-methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide, N-methyl-2-({3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide, Benzamide, N-methyl-2-((3-((E)-2-(2-pyridinyl)ethenyl)-1H-indazol-6-yl)thio)-, N-methyl-2-({3-[(1E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide, Benzamide, N-methyl-2-((3-((1E)-2-(2-pyridinyl)ethenyl)-1H-indazo)-6-yl)thio)-, N-methyl-2-((3-((E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide, (E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide