BIIB-024

cas: 1096708-71-2 — see every product listed under this CAS number, including other names

BIIB-024 (CAS 1096708-71-2) is a chemical reagent available from Chemat. Available pack sizes: 10mg. Offered by: Biosynth.

brandBiosynth
catalog numberFB103923-10mg
cas1096708-71-2
size10mg
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Available pack sizes

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Biosynth 10mg price on request

properties

categoryResearch Chemicals
sub-category 1Sourcing
purityNo data
delivery time3-4 weeks
Structural formula: {0} (CAS {1})

TAK-580 is a 1,3-thiazolecarboxamide that is 2-[(1R)-1-aminoethyl]-1,3-thiazole-5-carboxylic acid in which the carboxy group undergoes formal condensation with the amino group of 5-chloro-4-(trifluoromethyl)pyridin-2-amine and in which the amino group undergoes formal condensation with the carboxy group of 6-amino-5-chloropyrimidine-4-carboxylic acid. It is a pan-RAF kinase inhibitor which is currently in clinical development for the treatment of radiographically recurrent or progressive low-grade glioma in children and young adults. It has a role as an antineoplastic agent, an apoptosis inducer and a B-Raf inhibitor. It is a secondary carboxamide, an organofluorine compound, an aminopyrimidine, a chloropyridine, a pyrimidinecarboxamide and a 1,3-thiazolecarboxamide.

Source: ChEBI

Identity
Molecular formulaC17H12Cl2F3N7O2S
Molecular weight506.3 g/mol
IUPAC name2-[(1R)-1-[(6-amino-5-chloropyrimidine-4-carbonyl)amino]ethyl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide
InChIKeyVWMJHAFYPMOMGF-ZCFIWIBFSA-N
SMILESC[C@H](C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)Cl

Computed by PubChem (NCBI)

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