MLN 2480
cas: 1096708-71-2 — see every product listed under this CAS number, including other names
MLN 2480 (CAS 1096708-71-2) is a chemical reagent available from Chemat. Available pack sizes: 2mg, 10mg, 100mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC11649-2 |
| cas | 1096708-71-2 |
| size | 2mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 2mg | 774.90 Pln | |
| GLPBio | 10mg | 1383.36 Pln | |
| GLPBio | 100mg | 6101.31 Pln | |
| GLPBio | 5mg | 962.12 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 1022.97 Pln | |
| GLPBio | 50mg | 3550.44 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
TAK-580 is a 1,3-thiazolecarboxamide that is 2-[(1R)-1-aminoethyl]-1,3-thiazole-5-carboxylic acid in which the carboxy group undergoes formal condensation with the amino group of 5-chloro-4-(trifluoromethyl)pyridin-2-amine and in which the amino group undergoes formal condensation with the carboxy group of 6-amino-5-chloropyrimidine-4-carboxylic acid. It is a pan-RAF kinase inhibitor which is currently in clinical development for the treatment of radiographically recurrent or progressive low-grade glioma in children and young adults. It has a role as an antineoplastic agent, an apoptosis inducer and a B-Raf inhibitor. It is a secondary carboxamide, an organofluorine compound, an aminopyrimidine, a chloropyridine, a pyrimidinecarboxamide and a 1,3-thiazolecarboxamide.
Source: ChEBI
| Molecular formula | C17H12Cl2F3N7O2S |
|---|---|
| Molecular weight | 506.3 g/mol |
| IUPAC name | 2-[(1R)-1-[(6-amino-5-chloropyrimidine-4-carbonyl)amino]ethyl]-N-[5-chloro-4-(trifluoromethyl)-2-pyridinyl]-1,3-thiazole-5-carboxamide |
| InChIKey | VWMJHAFYPMOMGF-ZCFIWIBFSA-N |
| SMILES | C[C@H](C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)Cl |
Computed by PubChem (NCBI)