CB–1158 (INCB01158)
cas: 2095732-06-0 — see every product listed under this CAS number, including other names
CB–1158 (INCB01158) (CAS 2095732-06-0) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 25mg, 5mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC33106-10 |
| cas | 2095732-06-0 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 2221.17 Pln | |
| GLPBio | 25mg | 3943.60 Pln | |
| GLPBio | 5mg | 1444.21 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Numidargistat is an aminopyrrolidine that is pyrrolidine substituted by (2S)-2-aminopropanoyl, amino, carboxy, and 3-boronopropyl groups at positions 1, 3, 3, and 4 (the 3R,4S-stereoisomer). It is a selective arginase inhibitor being developed by Calithera Biosciences for the treatment of solid tumours. It has a role as an EC 3.5.3.1 (arginase) inhibitor, an antineoplastic agent and an immunomodulator. It is a member of boronic acids, a N-acylpyrrolidine, a pyrrolidinecarboxylic acid, an aminopyrrolidine, a primary amino compound and an amino monocarboxylic acid.
Source: ChEBI
| Molecular formula | C11H22BN3O5 |
|---|---|
| Molecular weight | 287.12 g/mol |
| IUPAC name | (3R,4S)-3-amino-1-[(2S)-2-aminopropanoyl]-4-(3-boronopropyl)pyrrolidine-3-carboxylic acid |
| InChIKey | ZZJLMZYUGLJBSO-LAEOZQHASA-N |
| SMILES | B(CCC[C@H]1CN(C[C@]1(C(=O)O)N)C(=O)[C@H](C)N)(O)O |
Computed by PubChem (NCBI)