CB-1158

cas: 2095732-06-0 — see every product listed under this CAS number, including other names

CB-1158 (CAS 2095732-06-0) is a chemical reagent available from Chemat. Available pack sizes: 10g, 5g. Offered by: Biosynth.

brandBiosynth
catalog numberVID73206-10g
cas2095732-06-0
size10g
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Available pack sizes

brand size price
Biosynth 10g price on request
Biosynth 5g price on request

properties

categoryLife Sciences
sub-category 1Ligands
purityNo data
delivery time10-12 weeks
Structural formula: {0} (CAS {1})

Numidargistat is an aminopyrrolidine that is pyrrolidine substituted by (2S)-2-aminopropanoyl, amino, carboxy, and 3-boronopropyl groups at positions 1, 3, 3, and 4 (the 3R,4S-stereoisomer). It is a selective arginase inhibitor being developed by Calithera Biosciences for the treatment of solid tumours. It has a role as an EC 3.5.3.1 (arginase) inhibitor, an antineoplastic agent and an immunomodulator. It is a member of boronic acids, a N-acylpyrrolidine, a pyrrolidinecarboxylic acid, an aminopyrrolidine, a primary amino compound and an amino monocarboxylic acid.

Source: ChEBI

Identity
Molecular formulaC11H22BN3O5
Molecular weight287.12 g/mol
IUPAC name(3R,4S)-3-amino-1-[(2S)-2-aminopropanoyl]-4-(3-boronopropyl)pyrrolidine-3-carboxylic acid
InChIKeyZZJLMZYUGLJBSO-LAEOZQHASA-N
SMILESB(CCC[C@H]1CN(C[C@]1(C(=O)O)N)C(=O)[C@H](C)N)(O)O

Computed by PubChem (NCBI)

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