CCT251545, 99.39%
cas: 1661839-45-7 — see every product listed under this CAS number, including other names
CCT251545, 99.39% (CAS 1661839-45-7) is a chemical reagent available from Chemat. Available pack sizes: 50 mg, 25 mg, 5 mg, 100 mg, 10mM/1mL, 10 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-12681-50 mg |
| cas | 1661839-45-7 |
| size | 50 mg |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 50 mg | 2613.83 Pln | |
| MedChemExpress | 25 mg | 1657.16 Pln | |
| MedChemExpress | 5 mg | 598.33 Pln | |
| MedChemExpress | 100 mg | 4127.77 Pln | |
| MedChemExpress | 10mM/1mL | 649.42 Pln | |
| MedChemExpress | 10 mg | 886.26 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.39% |
CCT251545 is a chloropyridine that is 3-chloropyridine substituted by a 1-oxo-2,8-diazaspiro[4.5]decan-8-yl group and a 4-(1-methyl-1H-pyrazol-4-yl)phenyl group at positions 4 and 5, respectively. It is an orally bioavailable inhibitor of Wnt signaling (IC50 = 5 nM) and a potent and selective chemical probe for cyclin-dependent kinases CDK8 and CDK19. It has a role as an antineoplastic agent, a Wnt signalling inhibitor and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is a member of pyrazoles, an azaspiro compound and a chloropyridine.
Source: ChEBI
| Molecular formula | C23H24ClN5O |
|---|---|
| Molecular weight | 421.9 g/mol |
| IUPAC name | 8-[3-chloro-5-[4-(1-methylpyrazol-4-yl)phenyl]-4-pyridinyl]-2,8-diazaspiro[4.5]decan-1-one |
| InChIKey | LBFYQISQYCGDDW-UHFFFAOYSA-N |
| SMILES | CN1C=C(C=N1)C2=CC=C(C=C2)C3=CN=CC(=C3N4CCC5(CCNC5=O)CC4)Cl |
Computed by PubChem (NCBI)