Products 1661839-45-7
CAS 1661839-45-7 appears in our catalog under these names: Cct251545, 95%, CCT251545/ 99.37% (existing batch purity), CCT251545, CCT251545 98+%, CCT251545, 98+%, 98+%. Offered by: Combi-blocks, TargetMol, GLPBio, Biosynth, Ambeed. Available pack sizes: 250mg, 100mg, 1mg, 5mg, 10mg, 25mg, 50mg, 2mg.
CCT251545 is a chloropyridine that is 3-chloropyridine substituted by a 1-oxo-2,8-diazaspiro[4.5]decan-8-yl group and a 4-(1-methyl-1H-pyrazol-4-yl)phenyl group at positions 4 and 5, respectively. It is an orally bioavailable inhibitor of Wnt signaling (IC50 = 5 nM) and a potent and selective chemical probe for cyclin-dependent kinases CDK8 and CDK19. It has a role as an antineoplastic agent, a Wnt signalling inhibitor and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is a member of pyrazoles, an azaspiro compound and a chloropyridine.
Source: ChEBI
| Molecular formula | C23H24ClN5O |
|---|---|
| Molecular weight | 421.9 g/mol |
| IUPAC name | 8-[3-chloro-5-[4-(1-methylpyrazol-4-yl)phenyl]-4-pyridinyl]-2,8-diazaspiro[4.5]decan-1-one |
| InChIKey | LBFYQISQYCGDDW-UHFFFAOYSA-N |
| SMILES | CN1C=C(C=N1)C2=CC=C(C=C2)C3=CN=CC(=C3N4CCC5(CCNC5=O)CC4)Cl |
Computed by PubChem (NCBI)