CCT251545
cas: 1661839-45-7 — see every product listed under this CAS number, including other names
CCT251545 (CAS 1661839-45-7) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 2mg, 5mg, 10mM (in 1ml dmso), 50mg, 25mg. Offered by: GLPBio, Biosynth.
| brand | GLPBio |
|---|---|
| catalog number | GC17606-10 |
| cas | 1661839-45-7 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 1397.41 Pln | |
| GLPBio | 2mg | 737.45 Pln | |
| GLPBio | 5mg | 1004.24 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 962.12 Pln | |
| GLPBio | 50mg | 3363.22 Pln | |
| Biosynth | 50mg | price on request | |
| Biosynth | 25mg | price on request |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
CCT251545 is a chloropyridine that is 3-chloropyridine substituted by a 1-oxo-2,8-diazaspiro[4.5]decan-8-yl group and a 4-(1-methyl-1H-pyrazol-4-yl)phenyl group at positions 4 and 5, respectively. It is an orally bioavailable inhibitor of Wnt signaling (IC50 = 5 nM) and a potent and selective chemical probe for cyclin-dependent kinases CDK8 and CDK19. It has a role as an antineoplastic agent, a Wnt signalling inhibitor and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is a member of pyrazoles, an azaspiro compound and a chloropyridine.
Source: ChEBI
| Molecular formula | C23H24ClN5O |
|---|---|
| Molecular weight | 421.9 g/mol |
| IUPAC name | 8-[3-chloro-5-[4-(1-methylpyrazol-4-yl)phenyl]-4-pyridinyl]-2,8-diazaspiro[4.5]decan-1-one |
| InChIKey | LBFYQISQYCGDDW-UHFFFAOYSA-N |
| SMILES | CN1C=C(C=N1)C2=CC=C(C=C2)C3=CN=CC(=C3N4CCC5(CCNC5=O)CC4)Cl |
Computed by PubChem (NCBI)