CP 724714
cas: 383432-38-0 — see every product listed under this CAS number, including other names
CP 724714 (CAS 383432-38-0) is a chemical reagent available from Chemat. Available pack sizes: 250mg, 10mg, 50mg. Offered by: TRC, Biosynth.
| brand | TRC |
|---|---|
| catalog number | TRC-C781365-250MG |
| cas | 383432-38-0 |
| size | 250mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| TRC | 250mg | price on request | |
| Biosynth | 10mg | price on request | |
| Biosynth | 50mg | price on request |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
CP-724714 is a 2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide in which the double bond adopts a trans-configuration. It is a potent inhibitor of HER2/ErbB2 (IC50 = 10 nM) and exhibits anti-cancer activity. It has a role as an antineoplastic agent, a hepatotoxic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an apoptosis inducer.
Source: ChEBI
| Molecular formula | C27H27N5O3 |
|---|---|
| Molecular weight | 469.5 g/mol |
| IUPAC name | 2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]quinazolin-6-yl]prop-2-enyl]acetamide |
| InChIKey | LLVZBTWPGQVVLW-SNAWJCMRSA-N |
| SMILES | CC1=NC=C(C=C1)OC2=C(C=C(C=C2)NC3=NC=NC4=C3C=C(C=C4)/C=C/CNC(=O)COC)C |
Computed by PubChem (NCBI)