Products 383432-38-0

CAS 383432-38-0 appears in our catalog under these names: CP 724714, CP-724714/ 99.1% (existing batch purity), CP–724714, CP-724714, CP-724714 99%. Offered by: TRC, TargetMol, GLPBio, Biosynth, Chemat. Available pack sizes: 250mg, 1mg, 2mg, 5mg, 10mg, 25mg, 50mg, 100mg.

CP 724714
TRC, Biosynth
  • size: 250mg, 10mg, 50mg
  • Variants: 3
View product
CP-724714/ 99.1% (existing batch purity)
TargetMol
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 7
from 432.54
View product
CP–724714
GLPBio
  • size: 100mg, 25mg, 5mg, 10mM (in 1ml dmso)
  • Variants: 4
from 718.73
View product
CP-724714
Chemat
  • size: 10mg, 1mg, 5mg
  • Variants: 3
from 994.04
View product
CP-724714 99%
Ambeed
  • size: 1mg, 5mg, 10mg, 25mg
  • Variants: 6
from 170.12
View product
2-Methoxy-N-[(2e)-3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]acetamide, 99%, 99%
Chemat
  • size: 1mg, 5mg
  • Variants: 2
from 146.00
View product
CP-724714, 98.72%
MedChemExpress
  • size: 10 mg, 50 mg, 5 mg, 100 mg
  • Variants: 6
from 640.13
View product
Structural formula: {0} (CAS {1})

CP-724714 is a 2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide in which the double bond adopts a trans-configuration. It is a potent inhibitor of HER2/ErbB2 (IC50 = 10 nM) and exhibits anti-cancer activity. It has a role as an antineoplastic agent, a hepatotoxic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an apoptosis inducer.

Source: ChEBI

Identity
Molecular formulaC27H27N5O3
Molecular weight469.5 g/mol
IUPAC name2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]quinazolin-6-yl]prop-2-enyl]acetamide
InChIKeyLLVZBTWPGQVVLW-SNAWJCMRSA-N
SMILESCC1=NC=C(C=C1)OC2=C(C=C(C=C2)NC3=NC=NC4=C3C=C(C=C4)/C=C/CNC(=O)COC)C

Computed by PubChem (NCBI)

Synonyms: orb1223133, orb1303306, cid_9874913, LLVZBTWPGQVVLW-SNAWJCMRSA-N
Related forms of this compound
2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]quinazolin-6-yl]prop-2-enyl]acetamide C27H27N5O3