CP-724714

cas: 383432-38-0 — see every product listed under this CAS number, including other names

CP-724714 (CAS 383432-38-0) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 1mg, 5mg. Offered by: Chemat.

brandChemat
catalog numberCM32700W-10mg
cas383432-38-0
size10mg
Need more information?

Ask us about this product — we're happy to help.

Available pack sizes

brand size price
Chemat 10mg 2507.82 Pln
Chemat 1mg 994.04 Pln
Chemat 5mg 1534.66 Pln

properties

delivery time1-2 weeks
purityno data
categoryChemicals
Structural formula: {0} (CAS {1})

CP-724714 is a 2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide in which the double bond adopts a trans-configuration. It is a potent inhibitor of HER2/ErbB2 (IC50 = 10 nM) and exhibits anti-cancer activity. It has a role as an antineoplastic agent, a hepatotoxic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an apoptosis inducer.

Source: ChEBI

Identity
Molecular formulaC27H27N5O3
Molecular weight469.5 g/mol
IUPAC name2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]quinazolin-6-yl]prop-2-enyl]acetamide
InChIKeyLLVZBTWPGQVVLW-SNAWJCMRSA-N
SMILESCC1=NC=C(C=C1)OC2=C(C=C(C=C2)NC3=NC=NC4=C3C=C(C=C4)/C=C/CNC(=O)COC)C

Computed by PubChem (NCBI)

Also listed as