Ciclosporin

cas: 59865-13-3 — see every product listed under this CAS number, including other names

Ciclosporin (CAS 59865-13-3) is a chemical reagent available from Chemat. Available pack sizes: 250mg, 1EA. Offered by: Mikromol, Sigma-Aldrich.

brandMikromol
catalog numberMM0241.00
cas59865-13-3
size250mg
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Available pack sizes

brand size price
Mikromol 250mg price on request
Sigma-Aldrich 1EA 665.70 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Cyclosporin A is a cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle. It has a role as an anticoronaviral agent, a geroprotector, a metabolite, an immunosuppressive agent, an antifungal agent, an antirheumatic drug, an EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor, an anti-asthmatic drug, a dermatologic drug and a carcinogenic agent.

Source: ChEBI

Identity
Molecular formulaC62H111N11O12
Molecular weight1202.6 g/mol
IUPAC name(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
InChIKeyPMATZTZNYRCHOR-CGLBZJNRSA-N
SMILESCC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C

Computed by PubChem (NCBI)

Synonyms: cyclosporin A, Ciclosporin, cyclosporine, Sandimmune, Neoral, Sandimmun, Cyclosporine A, Ciclosporine, Neoplanta, Equoral
Related forms of this compound
30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone C62H111N11O12
(3R,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone C62H111N11O12
Isomers (same molecular formula)
(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S,34R)-30-ethyl-34-[(E,2R)-hex-4-en-2-yl]-4,7,10,12,15,19,25,28-octamethyl-33-(methylamino)-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1-oxa-4,7,10,13,16,19,22,25,28,31-decazacyclotetratriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone C62H111N11O12

Also listed as

Cyclosporin A, min. 95 %, 10 g Roth CAS 59865-13-3
Cyclosporin A (Cyclosporine) Chemat Brand CAS 59865-13-3
Cyclosporin A, >95% (HPLC) TRC CAS 59865-13-3
Cyclosporin A, 99% AmBeed CAS 59865-13-3
Cyclosporin A Dr. Ehrenstorfer CAS 59865-13-3
Cyclosporine GLPBio CAS 59865-13-3
Cyclosporin A GLPBio CAS 59865-13-3
Cyclosporin A, 99+% Thermo Scientific (Alfa Aesar) CAS 59865-13-3
Cyclosporin A, >97.0%(HPLC)(N) TCI CAS 59865-13-3
Cyclosporin A - Bio-X â„¢ Biosynth CAS 59865-13-3
Cyclosporin A, 98% Thermo Scientific (Acros) CAS 59865-13-3
Cyclosporin A, USP grade, 98.50% Chemat CAS 59865-13-3
Cyclosporin A, 98.50% Chemat CAS 59865-13-3
Cyclosporin A 97.0-101.5% (on dried bas& Sigma-Aldrich CAS 59865-13-3
CYCLOSPORIN A FROM TOLYPOCLADIUM INFLAT& Sigma-Aldrich CAS 59865-13-3
Cyclosporin A, 98%, 98% Chemat CAS 59865-13-3
Cyclosporin A, 99.94% MedChemExpress CAS 59865-13-3
Cyclosporin A (Standard), 99.99% MedChemExpress CAS 59865-13-3
Cyclosporin A, min. 95 %, 5 g Roth CAS 59865-13-3
Cyclosporin A, min. 95 %, 25 g Roth CAS 59865-13-3