Cyclosporine

cas: 59865-13-3 — see every product listed under this CAS number, including other names

Cyclosporine (CAS 59865-13-3) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 200mg, 10mM (in 1ml dmso), 500mg. Offered by: GLPBio.

brandGLPBio
catalog numberGC11328-100
cas59865-13-3
size100mg
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Available pack sizes

brand size price
GLPBio 100mg 583.00 Pln
GLPBio 200mg 662.57 Pln
GLPBio 10mM (in 1ml dmso) 601.72 Pln
GLPBio 500mg 868.51 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Cyclosporin A is a cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle. It has a role as an anticoronaviral agent, a geroprotector, a metabolite, an immunosuppressive agent, an antifungal agent, an antirheumatic drug, an EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor, an anti-asthmatic drug, a dermatologic drug and a carcinogenic agent.

Source: ChEBI

Identity
Molecular formulaC62H111N11O12
Molecular weight1202.6 g/mol
IUPAC name(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
InChIKeyPMATZTZNYRCHOR-CGLBZJNRSA-N
SMILESCC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C

Computed by PubChem (NCBI)

Synonyms: cyclosporin A, Ciclosporin, cyclosporine, Sandimmune, Neoral, Sandimmun, Cyclosporine A, Ciclosporine, Neoplanta, Equoral
Related forms of this compound
30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone C62H111N11O12
(3R,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone C62H111N11O12
Isomers (same molecular formula)
(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S,34R)-30-ethyl-34-[(E,2R)-hex-4-en-2-yl]-4,7,10,12,15,19,25,28-octamethyl-33-(methylamino)-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1-oxa-4,7,10,13,16,19,22,25,28,31-decazacyclotetratriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone C62H111N11O12

Also listed as

Cyclosporin A, min. 95 %, 10 g Roth CAS 59865-13-3
Cyclosporin A (Cyclosporine) Chemat Brand CAS 59865-13-3
Cyclosporin A, >95% (HPLC) TRC CAS 59865-13-3
Cyclosporin A, 99% AmBeed CAS 59865-13-3
Ciclosporin Mikromol CAS 59865-13-3
Cyclosporin A Dr. Ehrenstorfer CAS 59865-13-3
Cyclosporin A GLPBio CAS 59865-13-3
Cyclosporin A, 99+% Thermo Scientific (Alfa Aesar) CAS 59865-13-3
Cyclosporin A, >97.0%(HPLC)(N) TCI CAS 59865-13-3
Cyclosporin A - Bio-X â„¢ Biosynth CAS 59865-13-3
Cyclosporin A, 98% Thermo Scientific (Acros) CAS 59865-13-3
Cyclosporin A, USP grade, 98.50% Chemat CAS 59865-13-3
Cyclosporin A, 98.50% Chemat CAS 59865-13-3
Cyclosporin A 97.0-101.5% (on dried bas& Sigma-Aldrich CAS 59865-13-3
CYCLOSPORIN A FROM TOLYPOCLADIUM INFLAT& Sigma-Aldrich CAS 59865-13-3
Cyclosporin A, 98%, 98% Chemat CAS 59865-13-3
Cyclosporin A, 99.94% MedChemExpress CAS 59865-13-3
Cyclosporin A (Standard), 99.99% MedChemExpress CAS 59865-13-3
Cyclosporin A, min. 95 %, 5 g Roth CAS 59865-13-3
Cyclosporin A, min. 95 %, 25 g Roth CAS 59865-13-3