Clofarabine

cas: 123318-82-1 — see every product listed under this CAS number, including other names

Clofarabine (CAS 123318-82-1) is a chemical reagent available from Chemat. Available pack sizes: on request, 250mg, 10mg, 100mg, 25mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: Chemat Brand, Mikromol, GLPBio, Biosynth.

brand	Chemat Brand
catalog number	ULC11501
cas	123318-82-1
size	on request
availability	Do potwierdzenia przez Chemat\|To be confirmed by Chemat

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Available pack sizes

brand	size	price
Chemat Brand	on request	price on request
Mikromol	250mg	price on request
GLPBio	10mg	583.00 Pln
GLPBio	100mg	1144.66 Pln
GLPBio	25mg	737.45 Pln
GLPBio	5mg	522.15 Pln
GLPBio	10mM (in 1ml dmso)	601.72 Pln
GLPBio	50mg	934.04 Pln
Biosynth	1g	price on request
Biosynth	0,5g	price on request
Biosynth	2g	price on request
Biosynth	10g	price on request
Biosynth	5g	price on request
Sigma-Aldrich	25MG	2290.00 Pln
Sigma-Aldrich	5MG	559.00 Pln

properties

purity	No data
category	Chemicals
delivery time	To be confirmed by Chemat

Clofarabine is a purine nucleoside analogue consisting of a 6-amino-2-chloropurin-9-yl group attached to the 1beta position of 2'-deoxy-2'-fluoro-D-arabinofuranose. It is metabolized intracellularly to the active 5'-triphosphate metabolite, which inhibits DNA synthesisis and so stops the growth of cancer cells. Clofarabine is used as an antimetabolite antineoplastic agent in the treatment of relapsed or refractory acute lymphoblastic leukaemia. It has a role as an antimetabolite and an antineoplastic agent. It is a member of adenosines and an organofluorine compound.

Source: ChEBI

Identity
Molecular formula	C₁₀H₁₁ClFN₅O₃
Molecular weight	303.68 g/mol
IUPAC name	(2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
InChIKey	WDDPHFBMKLOVOX-AYQXTPAHSA-N
SMILES	C1=NC2=C(N=C(N=C2N1[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)F)Cl)N