Clofarabine, BioScience Grade, 10 mg

cas: 123318-82-1 — see every product listed under this CAS number, including other names

Clofarabine, BioScience Grade, 10 mg (CAS 123318-82-1) is a chemical reagent available from Chemat. Available pack sizes: 10mg. Offered by: Roth.

brandRoth
catalog numberROTH-2A2N.1
cas123318-82-1
size10mg
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Available pack sizes

brand size price
Roth 10mg 514.44 Pln

properties

delivery time2 week

Clofarabine is a purine nucleoside analogue consisting of a 6-amino-2-chloropurin-9-yl group attached to the 1beta position of 2'-deoxy-2'-fluoro-D-arabinofuranose. It is metabolized intracellularly to the active 5'-triphosphate metabolite, which inhibits DNA synthesisis and so stops the growth of cancer cells. Clofarabine is used as an antimetabolite antineoplastic agent in the treatment of relapsed or refractory acute lymphoblastic leukaemia. It has a role as an antimetabolite and an antineoplastic agent. It is a member of adenosines and an organofluorine compound.

Source: ChEBI

Identity
Molecular formulaC10H11ClFN5O3
Molecular weight303.68 g/mol
IUPAC name(2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
InChIKeyWDDPHFBMKLOVOX-AYQXTPAHSA-N
SMILESC1=NC2=C(N=C(N=C2N1[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)F)Cl)N

Computed by PubChem (NCBI)

Synonyms: Clofarabine, Clolar, Evoltra, Clofarex, Cl-F-Ara-A, CAFdA, clofarabina, clofarabinum, 2-Chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-6-amine, 9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-
Related forms of this compound
5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol C10H11ClFN5O3
Isomers (same molecular formula)
5-(6-amino-2-chloropurin-7-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol C10H11ClFN5O3
(2R,3R,4S,5S)-2-(6-amino-2-fluoropurin-9-yl)-5-(chloromethyl)oxolane-3,4-diol C10H11ClFN5O3
(2R,3S,4S,5R)-2-(2-amino-6-chloropurin-9-yl)-4-fluoro-5-(hydroxymethyl)oxolan-3-ol C10H11ClFN5O3

Also listed as

Clofarabine Chemat Brand CAS 123318-82-1
Clofarabine, >95% (HPLC) TRC CAS 123318-82-1
Clofarabine/ 100% TargetMol CAS 123318-82-1
2-Chloro-2'-arabino-fluoro-2'- Thermo Scientific (Alfa Aesar) CAS 123318-82-1
Clofarabine, >98.0%(HPLC) TCI CAS 123318-82-1
Clofarabine - Bio-X â„¢ Biosynth CAS 123318-82-1
Clofarabine 97% Ambeed CAS 123318-82-1
Clofarabine, 99.83% MedChemExpress CAS 123318-82-1
Clofarabine (Standard) MedChemExpress CAS 123318-82-1
CLOFARABINE, 98% Fluorochem CAS 123318-82-1

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