DMH 4

cas: 515880-75-8 — see every product listed under this CAS number, including other names

DMH 4 (CAS 515880-75-8) is a chemical reagent available from Chemat. Available pack sizes: 250mg. Offered by: TRC.

brandTRC
catalog numberTRC-D494150-250MG
cas515880-75-8
size250mg
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Available pack sizes

brand size price
TRC 250mg price on request

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

DMH4 is a pyrazolopyrimidine that is pyrazolo[1,5-a]pyrimidine substituted by phenyl and 4-[2-(morpholin-4-yl)ethoxy]phenyl groups at positions 3 and 6, respectively. It is an inhibitor of VEGFR-2 (IC50 = 0.16 M). It has a role as an antineoplastic agent, an angiogenesis inhibitor, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor, a vascular endothelial growth factor receptor antagonist and an apoptosis inducer. It is a member of benzenes, an aromatic ether, a pyrazolopyrimidine, a member of morpholines and a tertiary amino compound.

Source: ChEBI

Identity
Molecular formulaC24H24N4O2
Molecular weight400.5 g/mol
IUPAC name4-[2-[4-(3-phenylpyrazolo[1,5-a]pyrimidin-6-yl)phenoxy]ethyl]morpholine
InChIKeySKZQZGSPYYHTQG-UHFFFAOYSA-N
SMILESC1COCCN1CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=CC=C5)N=C3

Computed by PubChem (NCBI)

Synonyms: 4-[2-[4-(3-phenylpyrazolo[1,5-a]pyrimidin-6-yl)phenoxy]ethyl]morpholine, 4-[2-(4-{3-phenylpyrazolo[1,5-a]pyrimidin-6-yl}phenoxy)ethyl]morpholine, 6-[4-[2-(4-Morpholinyl)ethoxy]phenyl]-3-phenylpyrazolo[1,5-a]pyrimidine, pyrazolo[1,5-a]pyrimidine 4b, Dorsomorphin homologue 4, orb1704566, 4-(2-(4-(3-phenylpyrazolo[1,5- a]pyrimidin-6-yl)phenoxy)ethyl)morpholine, 6-{4-[2-(Morpholin-4-yl)ethoxy]phenyl}-3-phenylpyrazolo[1,5-a]pyrimidine
Isomers (same molecular formula)
(4R)-6-amino-4-[3-(hydroxymethyl)-5-phenylphenyl]-3-methyl-4-propan-2-yl-2H-pyrano[2,3-c]pyrazole-5-carbonitrile C24H24N4O2
(4S)-6-amino-4-[3-(hydroxymethyl)-5-phenylphenyl]-3-methyl-4-propan-2-yl-2H-pyrano[2,3-c]pyrazole-5-carbonitrile C24H24N4O2
6-(4-hydroxyphenyl)-5-methyl-2-phenyl-3-piperidin-1-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one C24H24N4O2
6-amino-4-[3-(hydroxymethyl)-5-phenylphenyl]-3-methyl-4-propan-2-yl-2H-pyrano[2,3-c]pyrazole-5-carbonitrile C24H24N4O2
5-(3-methoxyphenoxy)-2-N-(4-propan-2-ylphenyl)quinazoline-2,4-diamine C24H24N4O2
2-[[3-[[5-(2-methyl-3-phenylphenyl)-1,3,4-oxadiazol-2-yl]amino]phenyl]methylamino]ethanol C24H24N4O2
12,14-dimethyl-9-(4-propan-2-ylphenyl)-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione C24H24N4O2
N-[(4-ethoxy-3-methoxyphenyl)methyl]-N-methyl-2-pyridin-3-ylquinazolin-4-amine C24H24N4O2
2-[[4-[[5-(2-methyl-3-phenylphenyl)-1,3,4-oxadiazol-2-yl]amino]phenyl]methylamino]ethanol C24H24N4O2

Also listed as

DMH4/ 98.68% (existing batch purity) TargetMol CAS 515880-75-8
DMH4 GLPBio CAS 515880-75-8
DMH4, 98.98% MedChemExpress CAS 515880-75-8