Products 515880-75-8
CAS 515880-75-8 appears in our catalog under these names: DMH 4, DMH4/ 98.68% (existing batch purity), DMH4, DMH4, 98.98%. Offered by: TRC, TargetMol, GLPBio, Chemat, MedChemExpress. Available pack sizes: 250mg, 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 5 mg.
DMH4 is a pyrazolopyrimidine that is pyrazolo[1,5-a]pyrimidine substituted by phenyl and 4-[2-(morpholin-4-yl)ethoxy]phenyl groups at positions 3 and 6, respectively. It is an inhibitor of VEGFR-2 (IC50 = 0.16 M). It has a role as an antineoplastic agent, an angiogenesis inhibitor, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor, a vascular endothelial growth factor receptor antagonist and an apoptosis inducer. It is a member of benzenes, an aromatic ether, a pyrazolopyrimidine, a member of morpholines and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C24H24N4O2 |
|---|---|
| Molecular weight | 400.5 g/mol |
| IUPAC name | 4-[2-[4-(3-phenylpyrazolo[1,5-a]pyrimidin-6-yl)phenoxy]ethyl]morpholine |
| InChIKey | SKZQZGSPYYHTQG-UHFFFAOYSA-N |
| SMILES | C1COCCN1CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=CC=C5)N=C3 |
Computed by PubChem (NCBI)
Synonyms:
4-[2-[4-(3-phenylpyrazolo[1,5-a]pyrimidin-6-yl)phenoxy]ethyl]morpholine, 4-[2-(4-{3-phenylpyrazolo[1,5-a]pyrimidin-6-yl}phenoxy)ethyl]morpholine, 6-[4-[2-(4-Morpholinyl)ethoxy]phenyl]-3-phenylpyrazolo[1,5-a]pyrimidine, pyrazolo[1,5-a]pyrimidine 4b, Dorsomorphin homologue 4, orb1704566, 4-(2-(4-(3-phenylpyrazolo[1,5- a]pyrimidin-6-yl)phenoxy)ethyl)morpholine, 6-{4-[2-(Morpholin-4-yl)ethoxy]phenyl}-3-phenylpyrazolo[1,5-a]pyrimidine