Daprodustat(GSK1278863)
cas: 960539-70-2 — see every product listed under this CAS number, including other names
Daprodustat(GSK1278863) (CAS 960539-70-2) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 5mg, 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC16647-10 |
| cas | 960539-70-2 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 905.95 Pln | |
| GLPBio | 100mg | 2829.64 Pln | |
| GLPBio | 5mg | 737.45 Pln | |
| GLPBio | 50mg | 1968.43 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Daprodustat is a member of the class of barbiturates that is barbituric acid substituted by cyclohexyl groups at positions 1 and 3, and by a (carboxymethyl)aminocarbonyl group at position 5. It is an inhibitor of hypoxia-inducible factor prolyl hydroxylase developed by GlaxoSmithKline for the treatment of anaemia in patients with chronic kidney disease. It has a role as an EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor, an antiviral agent and an anti-anaemic agent. It is a secondary carboxamide, a N-acylglycine, a member of barbiturates and an oxo monocarboxylic acid.
Source: ChEBI
| Molecular formula | C19H27N3O6 |
|---|---|
| Molecular weight | 393.4 g/mol |
| IUPAC name | 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinane-5-carbonyl)amino]acetic acid |
| InChIKey | RUEYEZADQJCKGV-UHFFFAOYSA-N |
| SMILES | C1CCC(CC1)N2C(=O)C(C(=O)N(C2=O)C3CCCCC3)C(=O)NCC(=O)O |
Computed by PubChem (NCBI)
Synonyms:
Daprodustat, JESDUVROQ, Duvroq, daprodustatum, N-((1,3-Dicyclohexylhexahydro-2,4,6-trioxopyrimidin-5-yl)carbonyl)glycine, 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinan-5-yl)formamido]acetic acid, 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinane-5-carbonyl)amino]acetic acid, Glycine, N-((1,3-dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl)-, N-[(1,3-Dicyclohexylhexahydro-2,4,6-trioxopyrimidin-5-yl)carbonyl]glycine, 2-((1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinan-5-yl)formamido)acetic acid