Flavopiridol, 99.72%
cas: 146426-40-6 — see every product listed under this CAS number, including other names
Flavopiridol, 99.72% (CAS 146426-40-6) is a chemical reagent available from Chemat. Available pack sizes: 100 mg, 25 mg, 10mM/1mL, 50 mg, 5 mg, 500 mg, 10 mg, 1 g. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-10005-100 mg |
| cas | 146426-40-6 |
| size | 100 mg |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 100 mg | 2400.20 Pln | |
| MedChemExpress | 25 mg | 946.63 Pln | |
| MedChemExpress | 10mM/1mL | 468.30 Pln | |
| MedChemExpress | 50 mg | 1355.30 Pln | |
| MedChemExpress | 5 mg | 435.79 Pln | |
| MedChemExpress | 500 mg | 7220.68 Pln | |
| MedChemExpress | 10 mg | 561.18 Pln | |
| MedChemExpress | 1 g | 11539.60 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.72% |
Alvocidib is a synthetic dihydroxyflavone that is 5,7-dihydroxyflavone which is substituted by a 3-hydroxy-1-methylpiperidin-4-yl group at position 8 and by a chlorine at the 2' position (the ()-3S,4R stereoisomer). A cyclin-dependent kinase 9 (CDK9) inhibitor, it has been studied for the treatment of acute myeloid leukaemia, arthritis and atherosclerotic plaque formation. It has a role as an antineoplastic agent, an antirheumatic drug, an apoptosis inducer and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is a dihydroxyflavone, a hydroxypiperidine, a tertiary amino compound and a member of monochlorobenzenes. It is a conjugate base of an alvocidib(1+).
Source: ChEBI
| Molecular formula | C21H20ClNO5 |
|---|---|
| Molecular weight | 401.8 g/mol |
| IUPAC name | 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]chromen-4-one |
| InChIKey | BIIVYFLTOXDAOV-YVEFUNNKSA-N |
| SMILES | CN1CC[C@@H]([C@@H](C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O |
Computed by PubChem (NCBI)