Fludarabine Phosphate, >95% (HPLC)

cas: 75607-67-9 — see every product listed under this CAS number, including other names

Fludarabine Phosphate, >95% (HPLC) (CAS 75607-67-9) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 1g. Offered by: TRC.

brandTRC
catalog numberTRC-F425005-100MG
cas75607-67-9
size100mg
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Available pack sizes

brand size price
TRC 100mg price on request
TRC 1g price on request

properties

purity>95% (HPLC)
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Fludarabine phosphate is a purine arabinonucleoside monophosphate having 2-fluoroadenine as the nucleobase. A prodrug, it is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. Once incorporated into DNA, 2-fluoro-ara-ATP functions as a DNA chain terminator. It is used for the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to, or whose disease has progressed during, treatment with at least one standard alkylating-agent containing regimenas. It has a role as an antiviral agent, an antimetabolite, an antineoplastic agent, an immunosuppressive agent, a prodrug and a DNA synthesis inhibitor. It is an organofluorine compound, a purine arabinonucleoside monophosphate and a nucleoside analogue. It is functionally related to a 2-fluoroadenine.

Source: ChEBI

Identity
Molecular formulaC10H13FN5O7P
Molecular weight365.21 g/mol
IUPAC name[(2R,3S,4S,5R)-5-(6-amino-2-fluoropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
InChIKeyGIUYCYHIANZCFB-FJFJXFQQSA-N
SMILESC1=NC2=C(N=C(N=C2N1[C@H]3[C@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)F)N

Computed by PubChem (NCBI)

Synonyms: fludarabine phosphate, fludara, Fludarabine 5'-monophosphate, Oforta, Fludarabine monophosphate, 2-F-ara-AMP, 2-Fluoro-9-(5-O-phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine, 2F-ara-AMP, 9-beta-D-Arabinofuranosyl-2-fluoroadenine 5'-(dihydrogen phosphate), 9H-Purin-6-amine, 2-fluoro-9-(5-O-phosphono-beta-D-arabinofuranosyl)-
Related forms of this compound
[(2R,3S,4R,5R)-5-(6-amino-2-fluoropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate C10H13FN5O7P
Isomers (same molecular formula)
[5-(2-amino-6-oxo-1H-purin-9-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate C10H13FN5O7P

Also listed as

Fludarabine Phosphate Mikromol CAS 75607-67-9
Fludarabine Phosphate/ 99.25% (existing batch purity) TargetMol CAS 75607-67-9
Fludarabine Phosphate (Fludara) GLPBio CAS 75607-67-9
Fludarabine Monophosphate, >98.0%(HPLC)(T) TCI CAS 75607-67-9
Fludarabine phosphate, 98.00% Chemat CAS 75607-67-9
Fludarabine (phosphate), 99.77% MedChemExpress CAS 75607-67-9
Fludarabine (phosphate) (Standard) MedChemExpress CAS 75607-67-9
Fludarabine phosphate, 98% Fluorochem CAS 75607-67-9
2-Fluoro-9-(5-O-phosphono-β-D-arabinofuranosyl)-9H-purin-6-amine, 98% Chemat CAS 75607-67-9
((2R,3S,4S,5R)-5-(6-Amino-2-fluoro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate, 98% BLDpharm CAS 75607-67-9