Fluorouracil
cas: 51-21-8 — see every product listed under this CAS number, including other names
Fluorouracil (CAS 51-21-8) is a chemical reagent available from Chemat. Available pack sizes: on request, 250mg, 10mg, 1EA, 500MG. Offered by: Chemat Brand, Mikromol, LoGiCal, Sigma-Aldrich.
| brand | Chemat Brand |
|---|---|
| catalog number | ULF536 |
| cas | 51-21-8 |
| size | on request |
| availability | Do potwierdzenia przez Chemat|To be confirmed by Chemat |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat Brand | on request | price on request | |
| Mikromol | 250mg | price on request | |
| LoGiCal | 10mg | price on request | |
| Sigma-Aldrich | 1EA | 665.70 Pln | |
| Sigma-Aldrich | 500MG | 849.40 Pln |
properties
| purity | No data |
|---|---|
| category | Chemicals |
| delivery time | To be confirmed by Chemat |
5-fluorouracil is a nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth. It has a role as a radiosensitizing agent, an antimetabolite, an antineoplastic agent, a xenobiotic, an immunosuppressive agent and an environmental contaminant. It is an organofluorine compound and a nucleobase analogue. It is functionally related to a uracil.
Source: ChEBI
| Molecular formula | C4H3FN2O2 |
|---|---|
| Molecular weight | 130.08 g/mol |
| IUPAC name | 5-fluoro-1H-pyrimidine-2,4-dione |
| InChIKey | GHASVSINZRGABV-UHFFFAOYSA-N |
| SMILES | C1=C(C(=O)NC(=O)N1)F |
Computed by PubChem (NCBI)
Synonyms:
5-Fluorouracil, fluorouracil, Efudex, Fluracil, Fluoroblastin, Carzonal, Queroplex, Fluril, Phthoruracil, Arumel