Products 51-21-8
CAS 51-21-8 appears in our catalog under these names: Fluorouracil, 5-Fluoro Uracil, >95% (HPLC), 5-Fluorouracil, Fluorouracil (Adrucil), 5-Fluorouracil, 99% . Offered by: Chemat Brand, TRC, Mikromol, LoGiCal, Dr. Ehrenstorfer. Available pack sizes: on request, 100g, 10g, 1g, 250mg, 10mg, 100mg, 200mg.
5-fluorouracil is a nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth. It has a role as a radiosensitizing agent, an antimetabolite, an antineoplastic agent, a xenobiotic, an immunosuppressive agent and an environmental contaminant. It is an organofluorine compound and a nucleobase analogue. It is functionally related to a uracil.
Source: ChEBI
| Molecular formula | C4H3FN2O2 |
|---|---|
| Molecular weight | 130.08 g/mol |
| IUPAC name | 5-fluoro-1H-pyrimidine-2,4-dione |
| InChIKey | GHASVSINZRGABV-UHFFFAOYSA-N |
| SMILES | C1=C(C(=O)NC(=O)N1)F |
Computed by PubChem (NCBI)
Synonyms:
5-Fluorouracil, fluorouracil, Efudex, Fluracil, Fluoroblastin, Carzonal, Queroplex, Fluril, Phthoruracil, Arumel