Fruquintinib, 98%

cas: 1194506-26-7 — see every product listed under this CAS number, including other names

Fruquintinib, 98% (CAS 1194506-26-7) is a chemical reagent available from Chemat. Available pack sizes: 25mg, 50mg, 100mg, 250mg, 1g. Offered by: Fluorochem.

brandFluorochem
catalog numberF826282-25MG
cas1194506-26-7
size25mg
availability In Stock China
Documents: Safety Data Sheet (MSDS)
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Available pack sizes

brand size price
Fluorochem 25mg 331.15 Pln
Fluorochem 50mg 549.82 Pln
Fluorochem 100mg 700.81 Pln
Fluorochem 250mg 1351.63 Pln
Fluorochem 1g 2273.18 Pln

properties

purity98%
dual useNo
currencyEUR
delivery time3-4 weeks
categoryOdczynniki chemiczne
Structural formula: {0} (CAS {1})

Fruquintinib is a member of the class of quinazolines that is quinazoline substituted by [2-methyl-3-(methylcarbamoyl)-1-benzofuran-6-yl]oxy, methoxy, and methoxy groups at positions 4, 6, and 7, respectively. It is a highly potent and selective inhibitor of VEGFR 1, 2 and 3 (IC50 = 33, 0.35, and 35 nM) used for the treatment of metastatic colorectal cancer. It has a role as an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and a vascular endothelial growth factor receptor antagonist. It is a secondary carboxamide, an aromatic ether, a member of quinazolines and a member of 1-benzofurans.

Source: ChEBI

Identity
Molecular formulaC21H19N3O5
Molecular weight393.4 g/mol
IUPAC name6-(6,7-dimethoxyquinazolin-4-yl)oxy-N,2-dimethyl-1-benzofuran-3-carboxamide
InChIKeyBALLNEJQLSTPIO-UHFFFAOYSA-N
SMILESCC1=C(C2=C(O1)C=C(C=C2)OC3=NC=NC4=CC(=C(C=C43)OC)OC)C(=O)NC

Computed by PubChem (NCBI)

Synonyms: Fruquintinib, Fruzaqla, 6-(6,7-dimethoxyquinazolin-4-yl)oxy-N,2-dimethyl-1-benzofuran-3-carboxamide, fruquintinibum, Elunate, 6-[(6,7-dimethoxyquinazolin-4-yl)oxy]-N,2-dimethyl-1-benzofuran-3-carboxamide, 6-(6,7-dimethoxyquinazolin-4-yloxy)-N,2-dimethylbenzofuran-3-carboxamide, 3-Benzofurancarboxamide, 6-((6,7-dimethoxy-4-quinazolinyl)oxy)-N,2-dimethyl-, 3-Benzofurancarboxamide, 6-[(6,7-dimethoxy-4-quinazolinyl)oxy]-N,2-dimethyl-, 6-((6,7-dimethoxyquinazolin-4-yl)oxy)-N,2-dimethyl-1-benzofuran-3-carboxamide
Related forms of this compound
6-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methyl-N-(trideuteriomethyl)-1-benzofuran-3-carboxamide C21H19N3O5
Isomers (same molecular formula)
prop-2-enyl N-[9-oxo-6-(prop-2-enoxycarbonylamino)-10H-acridin-3-yl]carbamate C21H19N3O5
2-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]oxyacetic acid C21H19N3O5
2-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]oxyacetic acid C21H19N3O5
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(2-oxo-1,3-dihydroimidazol-4-yl)propanoic acid C21H19N3O5
(2S)-10,18-dimethoxy-21-oxa-6,14,23-triazapentacyclo[12.9.0.02,6.08,13.016,22]tricosa-1(23),8(13),9,11,16(22),17,19-heptaene-7,15-dione C21H19N3O5

Also listed as

Fruquintinib/ 99.43% (existing batch purity) TargetMol CAS 1194506-26-7
Fruquintinib(HMPL–013) GLPBio CAS 1194506-26-7
Fruquintinib Biosynth CAS 1194506-26-7
Fruquintinib 98% Ambeed CAS 1194506-26-7
6-[(6,7-Dimethoxy-4-quinazolinyl)oxy]-N,2-dimethyl-3-benzofurancarboxamide, 98%, 98% Chemat CAS 1194506-26-7
Fruquintinib, 99.98% MedChemExpress CAS 1194506-26-7
Fruquintinib (Standard), 99.77% MedChemExpress CAS 1194506-26-7

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