Fruquintinib, 99.98%
cas: 1194506-26-7 — see every product listed under this CAS number, including other names
Fruquintinib, 99.98% (CAS 1194506-26-7) is a chemical reagent available from Chemat. Available pack sizes: 10mM/1mL, 100 mg, 10 mg, 5 mg, 50 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-19912-10mM/1mL |
| cas | 1194506-26-7 |
| size | 10mM/1mL |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 10mM/1mL | 440.44 Pln | |
| MedChemExpress | 100 mg | 1810.42 Pln | |
| MedChemExpress | 10 mg | 593.69 Pln | |
| MedChemExpress | 5 mg | 412.57 Pln | |
| MedChemExpress | 50 mg | 1072.02 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.98% |
Fruquintinib is a member of the class of quinazolines that is quinazoline substituted by [2-methyl-3-(methylcarbamoyl)-1-benzofuran-6-yl]oxy, methoxy, and methoxy groups at positions 4, 6, and 7, respectively. It is a highly potent and selective inhibitor of VEGFR 1, 2 and 3 (IC50 = 33, 0.35, and 35 nM) used for the treatment of metastatic colorectal cancer. It has a role as an antineoplastic agent, an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and a vascular endothelial growth factor receptor antagonist. It is a secondary carboxamide, an aromatic ether, a member of quinazolines and a member of 1-benzofurans.
Source: ChEBI
| Molecular formula | C21H19N3O5 |
|---|---|
| Molecular weight | 393.4 g/mol |
| IUPAC name | 6-(6,7-dimethoxyquinazolin-4-yl)oxy-N,2-dimethyl-1-benzofuran-3-carboxamide |
| InChIKey | BALLNEJQLSTPIO-UHFFFAOYSA-N |
| SMILES | CC1=C(C2=C(O1)C=C(C=C2)OC3=NC=NC4=CC(=C(C=C43)OC)OC)C(=O)NC |
Computed by PubChem (NCBI)
Synonyms:
Fruquintinib, Fruzaqla, 6-(6,7-dimethoxyquinazolin-4-yl)oxy-N,2-dimethyl-1-benzofuran-3-carboxamide, fruquintinibum, Elunate, 6-[(6,7-dimethoxyquinazolin-4-yl)oxy]-N,2-dimethyl-1-benzofuran-3-carboxamide, 6-(6,7-dimethoxyquinazolin-4-yloxy)-N,2-dimethylbenzofuran-3-carboxamide, 3-Benzofurancarboxamide, 6-((6,7-dimethoxy-4-quinazolinyl)oxy)-N,2-dimethyl-, 3-Benzofurancarboxamide, 6-[(6,7-dimethoxy-4-quinazolinyl)oxy]-N,2-dimethyl-, 6-((6,7-dimethoxyquinazolin-4-yl)oxy)-N,2-dimethyl-1-benzofuran-3-carboxamide