Fumagillin, Aspergillus fumigatus

cas: 23110-15-8 — see every product listed under this CAS number, including other names

Fumagillin, Aspergillus fumigatus (CAS 23110-15-8) is a chemical reagent available from Chemat. Available pack sizes: 500UG. Offered by: Sigma-Aldrich.

brandSigma-Aldrich
catalog number344845-500UG
cas23110-15-8
size500UG
availability availability
Documents: Safety Data Sheet (MSDS)
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Available pack sizes

brand size price
Sigma-Aldrich 500UG 600.00 Pln

properties

purityNo data
delivery time1-2 weeks (only if in stock, to check click on availability)
Structural formula: {0} (CAS {1})

Fumagillin is a meroterpenoid resulting from the formal condensation of the hydroxy group of fumagillol with the carboxylic acid group of (all-E)-deca-2,4,6,8-tetraenedioic acid. Originally isolated from the fungus Aspergillus fumigatus, it is used for the control of Nosema infection in honey bees. It has a role as an antimicrobial agent, an antiprotozoal drug, an antibacterial drug, an angiogenesis inhibitor, a methionine aminopeptidase 2 inhibitor and a fungal metabolite. It is a spiro-epoxide, an organooxygen heterocyclic antibiotic, a carboxylic ester, a dicarboxylic acid monoester, a meroterpenoid and an antibiotic antifungal drug. It is functionally related to a fumagillol and an (all-E)-deca-2,4,6,8-tetraenedioic acid.

Source: ChEBI

Identity
Molecular formulaC26H34O7
Molecular weight458.5 g/mol
IUPAC name(2E,4E,6E,8E)-10-[[(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl]oxy]-10-oxodeca-2,4,6,8-tetraenoic acid
InChIKeyNGGMYCMLYOUNGM-CSDLUJIJSA-N
SMILESCC(=CC[C@@H]1[C@@](O1)(C)[C@H]2[C@@H]([C@@H](CC[C@]23CO3)OC(=O)/C=C/C=C/C=C/C=C/C(=O)O)OC)C

Computed by PubChem (NCBI)

Synonyms: fumagillin, Fugillin, Fumidil, Amebacilin, Fumagilina, Fumagilline, Fumagillinum, Fumagillina, Fumidil-B, (-)-Fumagillin
Isomers (same molecular formula)
[2-[(1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxoethyl] acetate C26H34O7
[2-[(6S,8S,9S,10R,11S,13S,14S,17R)-17-acetyloxy-11-hydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate C26H34O7
5059-58-5 C26H34O7
[(1R,2S,4R,5R,6R,7R,10S,11R,14S,16S)-14,16-dihydroxy-7,11-dimethyl-6-(6-oxopyran-3-yl)-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-5-yl] acetate C26H34O7

Also listed as

Fumagillin, 95% Combi-blocks CAS 23110-15-8
Fumagillin Creative Peptides CAS 23110-15-8
Fumagillin/ min. 98% TargetMol CAS 23110-15-8
Fumagillin , 95.00% Chemat CAS 23110-15-8
Fumagillin 98% Ambeed CAS 23110-15-8
FUMAGILLIN FROM ASPERGILLUS FUMIGATUS Sigma-Aldrich CAS 23110-15-8
Fumagillin (Standard) MedChemExpress CAS 23110-15-8
Fumagillin, 99.0% MedChemExpress CAS 23110-15-8